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Mouse Respiratory Development Fibroblast Growth Factor Signaling

Signaling (Fgf10-Fgfr2b) in lung bud morphogenesis.

A. Lung budding results from mesodermal induction of Fgf10 and activation of Fgfr2b signaling in the Titf1-expressing endoderm at the prospective lung field.

B. Fgf10 and Fgfr2b expression in the E9.5 lung primordium by in situ hybridization. (Fgf10, mesoderm associated with emerging lung buds; Fgfr2b, lung endoderm).

C. Diagram representing known or putative regulators of Fgf10 expression in the developing lung; see text for details and references. Modified from Cardoso and Lu (2006).

Original file name: Figure 4. Cardoso04.jpg http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=stembook&part=specificationandpatterning&rendertype=figure&id=specificationandpatterning.F4

Reference

StemBook - Specification and patterning of the respiratory system

Copyright

© 2008 Wellington V. Cardoso and Darrell N. Kotton. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Cite this page: Hill, M.A. (2026, October 20) Embryology Mouse- respiratory development 04.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse-_respiratory_development_04.jpg

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current	07:53, 11 November 2010		800 × 728 (73 KB)	S8600021 (talk \| contribs)	==Mouse Respiratory Development Fibroblast Growth Factor Signaling== Signaling (Fgf10-Fgfr2b) in lung bud morphogenesis. A. Lung budding results from mesodermal induction of Fgf10 and activation of Fgfr2b signaling in the Titf1-expressing endoderm at th

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 <pubmed>20614584</pubmed>
-Cardoso WV, Kotton DN. '''Specification and patterning of the respiratory system.''' StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008 Jul 16. [http://www.ncbi.nlm.nih.gov/pubmed/20614584 PMID20614584] | [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=stembook&part=specificationandpatterning StemBook - Specification and patterning of the respiratory system]
+[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=stembook&part=specificationandpatterning StemBook - Specification and patterning of the respiratory system]
 ====Copyright====
 © 2008 Wellington V. Cardoso and Darrell N. Kotton.
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-[[Category:Mouse]] [[Category:Respiratory]] [[Category:Mouse E9.5]]
+[[Category:Mouse]] [[Category:Respiratory]] [[Category:Mouse E9.5]][[Category:FGF]]