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==Epigenetic Mechanisms==
==Epigenetic Mechanisms==


Epigenetics are as the name implies, inheritance mechanisms that lie outside the DNA sequence of our genes. One of the initial discoveries was the effects of DNA methylation upon gene expression and then modifications of nucleosomal histones. This DNA methylation, usually associated with 5-methylcytosine (m5C), leads to transcriptional silencing in vertebrates.
Epigenetics are inheritance mechanisms that lie outside the DNA sequence of our genes.  
 
* DNA methylation - usually associated with 5-methylcytosine (m5C), leads to transcriptional silencing in vertebrates.
* Modification of nucleosomal histones.  


===Reference===
===Reference===

Revision as of 16:04, 14 Haziran 2012

Epigenetic Mechanisms

Epigenetics are inheritance mechanisms that lie outside the DNA sequence of our genes.

  • DNA methylation - usually associated with 5-methylcytosine (m5C), leads to transcriptional silencing in vertebrates.
  • Modification of nucleosomal histones.

Reference

<pubmed>16688142</pubmed>


Image: Nature 441, 143-145 (11 May 2006), with permission.

http://www.nature.com/nature/journal/v441/n7090/full/441143a.html

File history

Yi efo/eka'e gwa ebo wo le nyangagi wuncin ye kamina wunga tinya nan

GwalagizhiNyangagiDimensionsUserComment
current12:52, 29 Haziran 2010Thumbnail for version as of 12:52, 29 Haziran 2010500 × 684 (53 KB)S8600021 (talk | contribs)Epigenetic Mechanisms Epigenetics are as the name implies, inheritance mechanisms that lie outside the DNA sequence of our genes. One of the initial discoveries was the effects of DNA methylation upon gene expression and then modifications of nucleosomal