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Epigenetics are as the name implies, inheritance mechanisms that lie outside the DNA sequence of our genes. One of the initial discoveries was the effects of DNA methylation upon gene expression and then modifications of nucleosomal histones. This DNA methylation, usually associated with 5-methylcytosine (m5C), leads to transcriptional silencing in vertebrates. | Epigenetics are as the name implies, inheritance mechanisms that lie outside the DNA sequence of our genes. One of the initial discoveries was the effects of DNA methylation upon gene expression and then modifications of nucleosomal histones. This DNA methylation, usually associated with 5-methylcytosine (m5C), leads to transcriptional silencing in vertebrates. | ||
===Reference=== | |||
<pubmed>16688142</pubmed> | |||
Image: Nature 441, 143-145 (11 May 2006), with permission. | Image: Nature 441, 143-145 (11 May 2006), with permission. | ||
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http://www.nature.com/nature/journal/v441/n7090/full/441143a.html | http://www.nature.com/nature/journal/v441/n7090/full/441143a.html | ||
[[Category:Molecular]] [[Category:Epigenetics]] | [[Category:Molecular]] [[Category:Epigenetics]] | ||
Revision as of 15:02, 14 June 2012
Epigenetic Mechanisms
Epigenetics are as the name implies, inheritance mechanisms that lie outside the DNA sequence of our genes. One of the initial discoveries was the effects of DNA methylation upon gene expression and then modifications of nucleosomal histones. This DNA methylation, usually associated with 5-methylcytosine (m5C), leads to transcriptional silencing in vertebrates.
Reference
<pubmed>16688142</pubmed>
Image: Nature 441, 143-145 (11 May 2006), with permission.
http://www.nature.com/nature/journal/v441/n7090/full/441143a.html
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Yi efo/eka'e gwa ebo wo le nyangagi wuncin ye kamina wunga tinya nan
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| current | 11:52, 29 June 2010 |  | 500 × 684 (53 KB) | S8600021 (talk | contribs) | Epigenetic Mechanisms Epigenetics are as the name implies, inheritance mechanisms that lie outside the DNA sequence of our genes. One of the initial discoveries was the effects of DNA methylation upon gene expression and then modifications of nucleosomal |
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