Mifepristone: Difference between revisions

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==Introduction==
==Introduction==
[[File:Mifepristone_molecular_structure.png|thumb|Mifepristone molecular structure]]
[[File:Mifepristone_molecular_structure.png|thumb|Mifepristone molecular structure]]
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:'''Links:''' [[Menstrual Cycle]]
:'''Links:''' [[Menstrual Cycle]]
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== Some Recent Findings ==
== Some Recent Findings ==

Revision as of 00:34, 14 December 2011

Educational Use Only - Embryology is an educational resource for learning concepts in embryological development, no clinical information is provided and content should not be used for any other purpose.

Introduction

Mifepristone molecular structure

(RU 486) A progesterone receptor antagonist similar in structure to the natural hormone progesterone, which is used medically as a birth control drug. Progesterone is a steroidal hormone of the progestogens class, which has many roles in the female. Functions include regulation of the menstrual cycle, uterine changes, maintaining pregnancy and effects on systems throughout the body. Biological sources include: adrenal glands, gonads (corpus luteum), brain, and placenta. Male progesterone has a suggested role in neural development. Progesterone is also used clinically as a part of hormone replacement therapy (HRT) in women. The human progesterone receptor has two isoforms (PRA and PRB). Commercial drug names include Mifegyne and Mifeprex.


Links: Menstrual Cycle

Some Recent Findings

  • Comparing two early medical abortion regimens: mifepristone+misoprostol vs. misoprostol alone[1] "Mifepristone+misoprostol is significantly more effective than use of misoprostol-alone for early medical abortion. The number of ongoing pregnancies documented with misoprostol-only warranted an early end of the trial after unblinding of the study at interim analysis. Policymakers should advocate for greater access to mifepristone. Future research should prioritize misoprostol-only regimens with shorter dosing intervals."

References

  1. ↑ <pubmed>21477682</pubmed>

Reviews

<pubmed>20933118</pubmed> <pubmed>20102310</pubmed> <pubmed>20004266</pubmed>

Articles

Search Pubmed

Search Pubmed: Mifepristone | 486 RU 486

Glossary Links

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Cite this page: Hill, M.A. (2024, June 26) Embryology Mifepristone. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Mifepristone

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
Retrieved from ‘https://embryology.med.unsw.edu.au/embryology/index.php?title=Mifepristone&oldid=81820’
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