Genetics - Chromosome 5: Difference between revisions
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===Development Genes=== | ===Development Genes=== | ||
* [https://www.omim.org/entry/600584 NKX2-5] - ( | * [https://www.omim.org/entry/600584 NKX2-5] - ({{Chr5}}q35.1) Homeobox-containing gene expressed only in the heart. | ||
* [https://www.omim.org/entry/600354 SMN1] - ({{Chr5}}q13) 38 kD protein expressed in neuronal cytoplasm and nucleus. Nuclear SMN is located in 'GEMS' (Gemini of the coiled bodies) involved in mRNA metabolism. Mutation or deletion of this gene causes {{Spinal muscular atrophy}} ({{SMA}}). | |||
==External Links== | ==External Links== |
Latest revision as of 11:51, 15 October 2018
Introduction
Chromosome territories (interphase) | Chromosome (Chromatin) structure (mitosis) |
Human Chromosomes: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | X | Y |
Some Recent Findings
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More recent papers |
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This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: Chromosome 5 <pubmed limit=5>Chromosome 5</pubmed> |
Development Genes
- NKX2-5 - (5q35.1) Homeobox-containing gene expressed only in the heart.
- SMN1 - (5q13) 38 kD protein expressed in neuronal cytoplasm and nucleus. Nuclear SMN is located in 'GEMS' (Gemini of the coiled bodies) involved in mRNA metabolism. Mutation or deletion of this gene causes Spinal muscular atrophy (SMA).
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
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Idiogram Chromosome Banding - The term refers to the light and dark pattern, seen after staining with a dye, of individual chromosomes identified in metaphase. It is only in meiosis and mitosis during metaphase that chromosomes can be easily identified, during the normal cell life (interphase) the chromosomes are unravelled and distributed within the nucleus in chromosome territories. A band is that part of a chromosome which is clearly distinguishable from nearby regions by appearing darker or brighter with one or more banding techniques. | |
Genetic abnormality locations: 1-4 | 5-8 | 9-12 | 13-16 | 17-20 | 21-XY | sSMC | |
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Links: Genetics | Abnormal Development - Genetic |
Cite this page: Hill, M.A. (2024, June 19) Embryology Genetics - Chromosome 5. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Genetics_-_Chromosome_5
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
Cite this page: Hill, M.A. (2024, June 19) Embryology Genetics - Chromosome 5. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Genetics_-_Chromosome_5
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G