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Primordial Germ Cell DNA Methylation

Nuclear distribution of H3K79me2 and H3K79me3 in fetal germ cells.

H3K79me2 and H3K79me3 are associated with the DNA-unmethylated and methylated alleles of differentially methylated regions (DMRs)

Female and male germ cells (FGC and MGC, respectively) and female somatic cells (SC) at 15.5 dpc were stained with the H3K79me2 and H3K79me3 antibodies as indicated and are shown in the different channels separately and in red-blue composite.

(A) DAPI-stained chromocenters are excluded from H3K79me2 signals (open arrowheads).

(B) DAPI-rich chromocenters colocalize with H3K79me3 signals (closed arrowheads).

Links: Primordial Germ Cell Development

Figure 9. Journal.pone.0023848.g009.jpg

Reference

Abe M, Tsai SY, Jin SG, Pfeifer GP & Szabó PE. (2011). Sex-specific dynamics of global chromatin changes in fetal mouse germ cells. PLoS ONE , 6, e23848. PMID: 21886830 DOI.

Copyright

© 2011 Abe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cite this page: Hill, M.A. (2024, June 27) Embryology Primordial germ cell DNA methylation 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Primordial_germ_cell_DNA_methylation_01.jpg

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current	00:30, 23 September 2011		687 × 1,000 (70 KB)	S8600021 (talk \| contribs)	==Primordial Germ Cell DNA Methylation== Nuclear distribution of H3K79me2 and H3K79me3 in fetal germ cells. Female and male germ cells (FGC and MGC, respectively) and female somatic cells (SC) at 15.5 dpc were stained with the H3K79me2 and H3K79me3 anti

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 Nuclear distribution of H3K79me2 and H3K79me3 in fetal germ cells.
-Female and male germ cells (FGC and MGC, respectively) and female somatic cells (SC) at 15.5 dpc were stained with the H3K79me2 and H3K79me3 antibodies as indicated and are shown in the different channels separately and in red-blue composite. (A) DAPI-stained chromocenters are excluded from H3K79me2 signals (open arrowheads). (B) DAPI-rich chromocenters colocalize with H3K79me3 signals (closed arrowheads). Other details are as in legend to Figure 1.
+* H3K79me2 and H3K79me3 are associated with the DNA-unmethylated and methylated alleles of differentially methylated regions (DMRs)
+Female and male germ cells (FGC and MGC, respectively) and female somatic cells (SC) at 15.5 dpc were stained with the H3K79me2 and H3K79me3 antibodies as indicated and are shown in the different channels separately and in red-blue composite.
+(A) DAPI-stained chromocenters are excluded from H3K79me2 signals (open arrowheads).
+(B) DAPI-rich chromocenters colocalize with H3K79me3 signals (closed arrowheads).
-Figure 9. Journal.pone.0023848.g009.jpg
-===Reference===
+:'''Links:''' [[Primordial Germ Cell Development]]
- Abe M, Tsai SY, Jin S-G, Pfeifer GP, Szabó PE (2011) Sex-Specific Dynamics of Global Chromatin Changes in Fetal Mouse Germ Cells. PLoS ONE 6(8): e23848. doi:10.1371/journal.pone.0023848
-http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0023848
+Figure 9. Journal.pone.0023848.g009.jpg
+===Reference===
+{{#pmid:21886830}}
+====Copyright====
+© 2011 Abe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- © 2011 Abe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
+{{Footer}}