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Revision as of 12:03, 28 September 2015

News - Maternal Malaria Neuromuscular Development Effects

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Malaria (plasmodium falciparum) - 125 million pregnancies worldwide are at risk of malaria infection every year. A recent mouse model of maternal infection, without embryo infection, has shown effects on neurovasular development in the exposed offspring.

(More? PMID 26402732 | Abnormal Development - Malaria)

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-| colspan=2|<span style="font-size:150%">'''News - Oocyte/Spermatozoa fate decision by Primordial Germ Cells'''</span>
+| colspan=2|<span style="font-size:150%">'''News - Maternal Malaria Neuromuscular Development Effects'''</span>
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-| valign=top|[[File:Medaka.jpg|alt=Medaka|link=Medaka Development|250px|left]][[File:Frazer002 bw600.jpg|150px|left]]
+| valign=top|[[File:Mouse E18 neurovasculature MicroCT.jpg|}600px]]
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-[[Medaka Development|'''Medaka''']] '''Sex determination is an essential step in the commitment of a germ cell to a spermatozoa or oocyte.''' The intrinsic factors that determine the sexual fate of vertebrate germ cells are unknown. "foxl3 (Forkhead Transcription Factor l3, an ancient duplicated copy of [http://omim.org/entry/605597?search=foxl2&highlight=foxl2 foxl2])  is expressed in germ cells but not somatic cells in the gonad, and has been identified as involved in sperm-egg fate decision in medaka fish. Adult XX medaka with disrupted foxl3 developed functional sperm in the expanded germinal epithelium of a histologically functional ovary. In chimeric medaka, mutant germ cells initiated spermatogenesis in female wild-type gonad. These results indicate that a germ cell-intrinsic cue for the sperm-egg fate decision is present in medaka and that spermatogenesis can proceed in a female gonadal environment."  (More? PMID 26067255 | [[Medaka Development]] | [[Oocyte Development]] | [[Spermatozoa Development]])
+[[Abnormal Development - Malaria|'''Malaria''']] (''plasmodium falciparum'') - 125 million pregnancies worldwide are at risk of malaria infection every year. A recent mouse model of maternal infection, without embryo infection, has shown effects on neurovasular development in the exposed offspring.
+  (More? PMID 26402732 | [[Abnormal Development - Malaria]])
 [[Template_talk:Main_Page_News|Older News Articles]] [[Template_talk:Main_Page_News#April|Rubella eliminated in the Americas]] | [[Template_talk:Main_Page_News#February|Three-person embryos]] | 2014 Nobel Prize in Medicine -  [http://www.nobelprize.org/nobel_prizes/medicine/laureates/2014/press.html Neural Development] | [[Neural_-_Hippocampus_Development|Hippocampus Development]] | WHO - Trends in Maternal Mortality 1990 to 2013 - [[Statistics - Maternal Mortality]] | [http://www.who.int/reproductivehealth/publications/monitoring/maternal-mortality-2013/en WHO Report Page] | WHO polio - [[Abnormal Development - Polio Virus|Polio Virus]] | Trisomy 21 - [[Template_talk:Main_Page_News#March|Genome-wide Effects]]
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