Template:Main Page News: Difference between revisions

Revision as of 16:30, 15 June 2015

Oocyte/Spermatozoa fate decision by Primordial Germ Cells

"Sex determination is an essential step in the commitment of a germ cell to a sperm or egg. However, the intrinsic factors that determine the sexual fate of vertebrate germ cells are unknown. Here we show that foxl3, which is expressed in germ cells but not somatic cells in the gonad, is involved in sperm-egg fate decision in medaka fish. Adult XX medaka with disrupted foxl3 developed functional sperm in the expanded germinal epithelium of a histologically functional ovary. In chimeric medaka, mutant germ cells initiated spermatogenesis in female wild-type gonad. These results indicate that a germ cell-intrinsic cue for the sperm-egg fate decision is present in medaka and that spermatogenesis can proceed in a female gonadal environment."

(More? Medaka Development | Oocyte Development | Spermatozoa Development)

@@ Line 1: / Line 1: @@
 {|
 |-bgcolor="CEDFF2"
-| colspan=2|<span style="font-size:150%">'''Americas region is declared the world’s first to eliminate endemic transmission of rubella'''</span>
+| colspan=2|<span style="font-size:150%">'''Oocyte/Spermatozoa fate decision by Primordial Germ Cells'''</span>
 |-bgcolor="F5FAFF"
-| valign=top|[[File:Rubella virus 03.jpg|alt=Rubella Virions|link=Abnormal Development - Rubella Virus|250px|left]]
+| valign=top|[[File:Medaka.jpg|alt=Medaka|link=Medaka Development|250px|left]]
 |
-'''[[Abnormal Development - Rubella Virus|Rubella]] is a contagious viral disease that can cause multiple birth defects as well as fetal death when contracted by women during pregnancy.'''
+'''[[Medaka Development|Medaka]]
-"This achievement culminates a 15-year effort that involved widespread administration of the vaccine against measles, mumps and rubella (MMR) throughout the Western Hemisphere. The announcement comes as 45 countries and territories of the Americas are participating in the 13th annual Vaccination Week in the Americas (April 25 to May 2)." This follows the regional eradication of [[:File:Child smallpox.jpg|smallpox]] in 1971 and the elimination of [[Abnormal Development - Polio Virus|polio]] in 1994.
+:"Sex determination is an essential step in the commitment of a germ cell to a sperm or egg. However, the intrinsic factors that determine the sexual fate of vertebrate germ cells are unknown. Here we show that foxl3, which is expressed in germ cells but not somatic cells in the gonad, is involved in sperm-egg fate decision in medaka fish. Adult XX medaka with disrupted foxl3 developed functional sperm in the expanded germinal epithelium of a histologically functional ovary. In chimeric medaka, mutant germ cells initiated spermatogenesis in female wild-type gonad. These results indicate that a germ cell-intrinsic cue for the sperm-egg fate decision is present in medaka and that spermatogenesis can proceed in a female gonadal environment."
-:(More? [[Abnormal Development - Rubella Virus|Rubella Virus]] | [http://www.paho.org/hq/index.php?option=com_content&view=article&id=10798%3Aamericas-free-of-rubella&Itemid=1926&lang=en WHO/PAHO Announcement])
+:(More? [[Medaka Development]] | [[Oocyte Development]] | [[Spermatozoa Development]])
 [[Template_talk:Main_Page_News|Older News Articles]] [[Template_talk:Main_Page_News#February|Three-person embryos]] | 2014 Nobel Prize in Medicine -  [http://www.nobelprize.org/nobel_prizes/medicine/laureates/2014/press.html Neural Development] | [[Neural_-_Hippocampus_Development|Hippocampus Development]] | WHO - Trends in Maternal Mortality 1990 to 2013 - [[Statistics - Maternal Mortality]] | [http://www.who.int/reproductivehealth/publications/monitoring/maternal-mortality-2013/en WHO Report Page] | WHO polio - [[Abnormal Development - Polio Virus|Polio Virus]] | Trisomy 21 - [[Template_talk:Main_Page_News#March|Genome-wide Effects]]
 |}<noinclude>[[Category:Template]][[Category:2015]]</noinclude>