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Embryo Epigenetics

Embryos Reprogram their Epigenetics

Two recent studies show that after fertilisation human embryos loose DNA methylation from most of the genome. This implies that there is an early "reprogramming" or "resetting" of the embryo's epigenetic status.

(More? Epigenetics | Nature. 2014 Jul PMID 25079558 PMID 25079557)

Older News Articles

WHO - Trends in Maternal Mortality 1990 to 2013. Statistics - Maternal Mortality | WHO Report Page
The World Health Organization says polio has re-emerged as a public health emergency. Polio Virus
Trisomy 21 Genome-wide Effects
RIKEN Panel Finds Misconduct in Reprogrammed Stem Cell Papers press release April 1, 2014 | Science April 2014

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-| colspan=2|<span style="font-size:150%">'''Maternal Mortality'''</span>
+| colspan=2|<span style="font-size:150%">'''Embryo Epigenetics'''</span>
 |-bgcolor="F5FAFF"
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-[[File:WHO map maternal mortality ratio 2013.jpg|250px|left]]
+[[File:Epigenetics_cartoon.jpg|250px|left]]
-| '''WHO - Trends in Maternal Mortality 1990 to 2013'''
+| '''Embryos Reprogram their Epigenetics'''
-An estimated 289,000 women died in 2013 due to complications in pregnancy and childbirth, down from 523,000 in 1990.
+Two recent studies show that after fertilisation human embryos loose DNA methylation from most of the genome. This implies that there is an early "reprogramming" or "resetting" of the embryo's epigenetic status.
-* more than 1 in 4 maternal deaths are caused by pre-existing medical conditions such as [[Abnormal_Development_-_Maternal_Diabetes |diabetes]], [[Abnormal_Development_-_Human_Immunodeficiency_Virus|HIV]], [[Abnormal_Development_-_Malaria|malaria]] and obesity, whose health impacts can all be aggravated by pregnancy. A related WHO study of causes of more than 60 000 maternal deaths in 115 countries caused 28% of the deaths.
-* Similar to the proportion of deaths during pregnancy and childbirth from severe bleeding.
-:(More? [[Statistics - Maternal Mortality]] | [http://www.who.int/reproductivehealth/publications/monitoring/maternal-mortality-2013/en WHO Report Page])
+:(More? [[Molecular Development - Epigenetics|Epigenetics]] | Nature. 2014 Jul PMID 25079558 PMID 25079557)
 [[Template_talk:Main_Page_News|Older News Articles]]
+* WHO - Trends in Maternal Mortality 1990 to 2013. [[Statistics - Maternal Mortality]] | [http://www.who.int/reproductivehealth/publications/monitoring/maternal-mortality-2013/en WHO Report Page]
 * The World Health Organization says polio has re-emerged as a public health emergency.  [[Abnormal Development - Polio Virus|Polio Virus]]
 * Trisomy 21 [[Template_talk:Main_Page_News#March|Genome-wide Effects]]
 * RIKEN Panel Finds Misconduct in Reprogrammed Stem Cell Papers  [http://www.riken.jp/en/pr/press/2014/20140401_2/RIKEN press release April 1, 2014] | [http://news.sciencemag.org/asiapacific/2014/04/riken-panel-finds-misconduct-reprogrammed-stem-cell-papers Science April 2014]
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