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hypothalamus | ==Hypothalamus Development Gene Interaction Model== | ||
Summary of potential regulatory interaction model of gene regulation for neurogenesis in the hypothalamus revealed by in silico analysis and literature. | |||
A model of interaction between the negative regulators HES5 and HEY1 and the positive regulators ASCL1 and NHLH1 based on the literature and present data. Activations are identified with a red arrow and repressions are identified with a green barred line. The purple arrow refers to the activation of NOTCH receptor by its ligand DLL1. (Bertrand, 2002; Gohkle, 2008, Castro, 2011, de la Pompa 1997, and present data) [13,29,34,50]. | |||
:'''Links:''' [[Endocrine_-_Hypothalamus_Development|Hypothalamus]] | [[Developmental_Signals_-_Notch|Notch]] | |||
===Reference=== | |||
<pubmed>24360028</pubmed>| [http://www.neuraldevelopment.com/content/8//25 Neural Dev.] | |||
====Copyright==== | |||
© 2013 Ratié et al.; licensee BioMed Central Ltd. | |||
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | |||
Ratié et al. Neural Development 2013 8:25 doi:10.1186/1749-8104-8-25 | |||
1749-8104-8-25-5.jpg | 1749-8104-8-25-5.jpg | ||
[[Category:Neural]] [[Category:Hypothalamus]] [[Category:Molecular]] [[Category:Notch]] | |||
Revision as of 22:52, 23 March 2014
Hypothalamus Development Gene Interaction Model
Summary of potential regulatory interaction model of gene regulation for neurogenesis in the hypothalamus revealed by in silico analysis and literature.
A model of interaction between the negative regulators HES5 and HEY1 and the positive regulators ASCL1 and NHLH1 based on the literature and present data. Activations are identified with a red arrow and repressions are identified with a green barred line. The purple arrow refers to the activation of NOTCH receptor by its ligand DLL1. (Bertrand, 2002; Gohkle, 2008, Castro, 2011, de la Pompa 1997, and present data) [13,29,34,50].
- Links: Hypothalamus | Notch
Reference
<pubmed>24360028</pubmed>| Neural Dev.
Copyright
© 2013 Ratié et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Ratié et al. Neural Development 2013 8:25 doi:10.1186/1749-8104-8-25
1749-8104-8-25-5.jpg
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