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The human fetus and placenta

Villous trophoblasts of the human placenta grow as a branched structure, maximising exchange with maternal blood. Extravillous trophoblast invade into the maternal endometrium, and some cells colonise maternal spiral arteries, expanding them to maximise blood flow. ♂ = Paternally expressed; ♀ = maternally expressed. Imprinted genes are important during fetal growth. Some, such as GNAS, UBE3A, and PLAGL, have physiological impact on the fetus only. Other genes may influence growth in utero via the placenta, or the fetus and placenta. The IUGR seen in SRS, and overgrowth in BWS are suggestive of a role of IGF2 in the human placenta.

Reference

Citation: Frost JM, Moore GE (2010) The Importance of Imprinting in the Human Placenta. PLoS Genet 6(7): e1001015. doi:10.1371/journal.pgen.1001015

Editor: Anne C. Ferguson-Smith, University of Cambridge, United Kingdom

Published: July 1, 2010

Copyright

© 2010 Frost, Moore. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Journal.pgen.1001015.g001.png

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1001015

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	Gwalagizhi	Nyangagi	Dimensions	User	Comment
current	08:45, 6 August 2010		600 × 452 (416 KB)	S8600021 (talk \| contribs)	Figure 1. The human fetus and placenta. Villous trophoblasts of the human placenta grow as a branched structure, maximising exchange with maternal blood. Extravillous trophoblast invade into the maternal endometrium, and some cells colonise maternal spir

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 Villous trophoblasts of the human placenta grow as a branched structure, maximising exchange with maternal blood. Extravillous trophoblast invade into the maternal endometrium, and some cells colonise maternal spiral arteries, expanding them to maximise blood flow. ♂ = Paternally expressed; ♀ = maternally expressed. Imprinted genes are important during fetal growth. Some, such as GNAS, UBE3A, and PLAGL, have physiological impact on the fetus only. Other genes may influence growth in utero via the placenta, or the fetus and placenta. The IUGR seen in SRS, and overgrowth in BWS are suggestive of a role of IGF2 in the human placenta.
-Journal.pgen.1001015.g001.png
+===Reference===
-http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1001015
 Citation: Frost JM, Moore GE (2010) The Importance of Imprinting in the Human Placenta. PLoS Genet 6(7): e1001015. doi:10.1371/journal.pgen.1001015
@@ Line 14: / Line 11: @@
 Published: July 1, 2010
-Copyright: © 2010 Frost, Moore. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
+====Copyright====
+© 2010 Frost, Moore. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
+Journal.pgen.1001015.g001.png
+http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1001015
 [[Category:Placenta]] [[Category:Molecular]] [[Category:Epigenetics]] [[Category:Imprinting]]