Talk:Skeletal Muscle Histology

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Cite this page: Hill, M.A. (2019, May 21) Embryology Skeletal Muscle Histology. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Skeletal_Muscle_Histology


Myogenesis

Somites in human embryo (Carnegie stage 11)

Three different types of muscle form in the body.

  • Skeletal muscle - cells originate from the paraxial mesoderm, forming somites, then dermamyotome and finally the myotome. Myoblasts undergo frequent divisions and coalesce with the formation of a multinucleated, syncytial muscle fibre or myotube. The nuclei of the myotube are still located centrally in the muscle fibre. In the course of the synthesis of the myofilaments/myofibrils, the nuclei are gradually displaced to the periphery of the cell.
  • Cardiac muscle - cells originate from the prechordal splanchnic mesoderm.
  • Smooth muscle - cells originate from undifferentiated mesenchymal cells. These cells differentiate first into mitotically active cells, myoblasts, which contain a few myofilaments. Myoblasts give rise to the cells which will differentiate into mature smooth muscle cells.