Paper - On a normal human ovum not over 7.5 days of age
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Hertig AT. and Rock J. On a normal ovum of approximately 9 to 10 days of age. (1945) Anat. Rec, 91: 281.
Hertig AT. and Rock J. On a human blastula recovered from the uterine cavity 4 days after ovulation. (1946) J Gerontol. 1(1): 96-117.
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On a Normal Human Ovum not over 7.5 days of Age
Free Hospital for Women, Brookline, Mass., Departments of Pathology, Obstetrics and Gynecology, Harvard Medical School and Department of Embryology, Carnegie Institution of Washington.
Abstract from the 1945 annual meeting of American Association of Anatomists
The ovum (Carnegie Embryo 8225) was discovered, after partial fixation, in a bicornuate uterus removed surgically on the twenty-second day of the cycle. Its implantation site was anterior, fundal, without vascular reaction, and just to 4he left of the midline (corpus luteum left). It appeared as a slightly raised but flattened, bowl-like object measuring 0.39 mm. in diame- ter, covered by a glistening membrane which partially concealed the eccentrically-situated 0.07 mm embryonic mass.
Microscopically, the endometrium is in the twenty-first day of its cycle with marked stromal edema and active glandular secretion. The chorion measures 0.120 X 0.306 X 0.330 mm; the chorionic cavity 0.030 X 0.200 X 0.228 mm; the embryo 0.036 X 0.078 X 0.090 mm and the amniotic cavity 0.006 X 0.054 X 0.060 mm The ovum, a two-thirds implanted blastacyst, possesses trophoblast similar to Carnegie 8020 and varies from a thin indifferent blastocyst wall (abembryonic pole) to a thick shell of primitive syncytio- and cytotrophoblast (embryonic pole). Active invasion and phagocytosis of maternal stroma by syncytiotrophoblast is a prominent feature.
The chorionic cavity is distorted and crowded by an eccentrically-placed, bilaminar germ disk. The amniotic cavity is merely an irregular slit between ectoderm and amnion, the latter arising from trophoblast. Mesoblasts, also apparently arising from trophoblast, are present at the embryonic pole but the exocoelomic membrane (Heuser’s) has not appeared.
Cite this page: Hill, M.A. (2019, June 25) Embryology Paper - On a normal human ovum not over 7.5 days of age. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Paper_-_On_a_normal_human_ovum_not_over_7.5_days_of_age
- © Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G