Template:Valproic Acid Teratogenic Dose table: Difference between revisions
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(Created page with "{| |+ Species Difference for Teratogenic Dose (lowest) mg/kg/day |-bgcolor="CEDFF2" | width=100px|'''Species''' | width=150px|'''Neural tube defects''' | width=150px|'''Skel...") |
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{| | {| | ||
|+ Species Difference for Teratogenic Dose (lowest) mg/kg/day | |+ '''Valproic Acid Species Difference for Teratogenic Dose''' (lowest) mg/kg/day | ||
|-bgcolor="CEDFF2" | |-bgcolor="CEDFF2" | ||
| width=100px|'''Species''' | | width=100px|'''Species''' | ||
| Line 7: | Line 7: | ||
| width=150px|'''Route''' | | width=150px|'''Route''' | ||
|- | |- | ||
| | | Human | ||
| 30 | | 30 | ||
| 20-30 | | 20-30 | ||
| Oral | | Oral | ||
|-bgcolor="F5FAFF" | |-bgcolor="F5FAFF" | ||
| | | {{monkey}} | ||
| not observed | | not observed | ||
| 150 | | 150 | ||
| oral | | oral | ||
|- | |- | ||
| | | {{rabbit}} | ||
| not observed | | not observed | ||
| 150 | | 150 | ||
| oral | | oral | ||
|-bgcolor="F5FAFF" | |-bgcolor="F5FAFF" | ||
| | | {{rat}} | ||
| not observed | | not observed | ||
| 150 | | 150 | ||
| oral | | oral | ||
|- | |- | ||
| | | {{hamster}} | ||
| 300 | | 300 | ||
| not investigated | | not investigated | ||
| ip | | ip | ||
|-bgcolor="F5FAFF" | |-bgcolor="F5FAFF" | ||
| | | {{mouse}} | ||
| 200 | | 200 | ||
| 200, 250, 400 | | 200, 250, 400 | ||
| ip, sc, oral | | ip, sc, oral | ||
|- | |- | ||
| colspan=4|Table Data{{#pmid:3104022|PMID3104022}} Links: {{drugs}} | | colspan=4|Table Data{{#pmid:3104022|PMID3104022}} Links: {{valproic acid}} | {{drugs}} | ||
|} | |} | ||
Latest revision as of 23:28, 6 June 2018
| Species | Neural tube defects | Skeletal defects | Route |
| Human | 30 | 20-30 | Oral |
| monkey | not observed | 150 | oral |
| rabbit | not observed | 150 | oral |
| rat | not observed | 150 | oral |
| hamster | 300 | not investigated | ip |
| mouse | 200 | 200, 250, 400 | ip, sc, oral |
| Table Data[1] Links: valproic acid | drugs | |||
