Template:Mouse Mammary Timeline table

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Mouse Mammary Timeline
Day Event
E10 milk line first formed by a slight thickening and stratification of the surface ectoderm.
Template:ME110.5 expression of Wnt10b in mammary lines on the trunk between the limbs and in axillary and inguinal streaks.
Template:ME111.5 milk line breaks up into individual placodes and the underlying mammary mesenchyme begins to condense.
Template:ME115.5 mammary epithelium begins to proliferate at the tip and the primary sprout pushes through the mammary mesenchyme towards the underlying fat pad.
Template:ME118.5 elongating duct has now grown into the fat pad and has branched into a small ductal system. Cells of the mammary mesenchyme have formed the nipple, which is made of specialized epidermal cells.
Data [1]   Related Images: E10/11 | E11 | E12 | E13 | E14.5
  1. Robinson GW. (2007). Cooperation of signalling pathways in embryonic mammary gland development. Nat. Rev. Genet. , 8, 963-72. PMID: 18007652 DOI.