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''"Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice."'' | ''"Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice."'' | ||
PMID 26808346 | [http:// | PMID 26808346 | [http://www.nature.com/nm/journal/v22/n3/full/nm.4030.html Nat Med.] | ||
Implanted in the intraperitoneal space of mice treated to chemically induce type 1 diabetes. Implants induced glycemic correction without any immunosuppression until their removal at 174 d after implantation. Human C-peptide concentrations and in vivo glucose responsiveness demonstrated therapeutically relevant glycemic control and retrieved implants contained viable insulin-producing cells. | Implanted in the intraperitoneal space of mice treated to chemically induce type 1 diabetes. Implants induced glycemic correction without any immunosuppression until their removal at 174 d after implantation. Human C-peptide concentrations and in vivo glucose responsiveness demonstrated therapeutically relevant glycemic control and retrieved implants contained viable insulin-producing cells. | ||
Revision as of 09:35, 24 March 2016
| News - Human Pancreas Stem Cells show Glycemic control in Mice |
PMID 26808346 | Nat Med. Implanted in the intraperitoneal space of mice treated to chemically induce type 1 diabetes. Implants induced glycemic correction without any immunosuppression until their removal at 174 d after implantation. Human C-peptide concentrations and in vivo glucose responsiveness demonstrated therapeutically relevant glycemic control and retrieved implants contained viable insulin-producing cells. |
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