Talk:Neural - Vascular Development: Difference between revisions
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Cite this page: Hill, M.A. (2024, April 26) Embryology Neural - Vascular Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Neural_-_Vascular_Development |
2016
Formation of the circle of Willis during human embryonic development
Congenit Anom (Kyoto). 2016 Mar 31. doi: 10.1111/cga.12165. [Epub ahead of print]
Takakuwa T1, Koike T1, Muranaka T1, Uwabe C2, Yamada S1,2.
Abstract
The circle of Willis (CW) is a circulatory anastomosis that supplies blood to the brain and adjacent structures. We examined the timing of formation of CW in 20 Japanese human embryo samples by using 3-dimensional reconstruction of serial histological sections. The CW was closed in 1 (n = 6), 2 (n = 8), 2 (n = 3) and 2 (n = 3) samples at Carnegie stages 20, 21, 22, and 23, respectively. The CW was unclosed in 13 samples (unclosed at ACOM alone, 6 samples; ACOM and bilateral P1, 4; left PCOM and right P1, 1; right PCOM and right P1, 1; ACOM and left PCOM, 1). It was difficult to predict whether the circle would close during further development, as such variations frequently exist in adults. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved. KEYWORDS: Circle of Willis; human embryo; three-dimensional reconstruction
PMID 27037515