Talk:Madrid Collection

Embryonic cardiac morphometry in Carnegie stages 15-23, from the Complutense University of Madrid Institute of Embryology Human Embryo Collection

Cells Tissues Organs. 2008;187(3):211-20. Epub 2007 Dec 5.

Arráez-Aybar LA1, Turrero-Nogués A, Marantos-Gamarra DG.

Abstract

AIMS: We performed a morphometric study of cardiac development on human embryos to complement the scarce data on human embryonic cardiac morphometry and to attempt to establish, from these, algorithms describing cardiac growth during the second month of gestation. METHODS: Thirty human embryos from Carnegie stages 15-23 were included in the study. Shrinkage and compression effects from fixation and inclusion in paraffin were considered in our calculations. RESULTS: Growth of the cardiac (whole heart) volume and volume of ventricular myocardium through the Carnegie stages were analysed by ANOVA. Linear correlation was used to describe the relationship between the ventricular myocardium and cardiac volumes. Comparisons of models were carried out through the R2 statistic. The relationship volume of ventricular myocardium versus cardiac volume is expressed by the equation: cardiac volume = 0.6266 + 2.4778 volume of ventricular myocardium. The relationship cardiac volume versus crown-rump length is expressed by the equation: cardiac volume = 1.3 e(0.126 CR length), where e is the base of natural logarithms. CONCLUSION: At a clinical level, these results can contribute towards the establishment of a normogram for cardiac development, useful for the design of strategies for early diagnosis of congenital heart disease. They can also help in the study of embryogenesis, for example in the discussion of ventricular trabeculation. Copyright 2007 S. Karger AG, Basel.

PMID 18057862

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The collection was started in 1935 by Professor Orts-Llorca (1905-1993) after its embryological formation in Paris with Henri Rouviere (1875-1952), in Brussels with Albert Dalcq (1893-1973), in Vienna with Alfred Fischel (1868-1938) and Munich with Walter Vogt (1888-1941) and Johannes Holtfreter (1901 - 1992). In Valencia live the Spanish Civil War (1936-39). In Cádiz (1939-1953) overcomes the difficulties associated with it, which did not prevent him form his collection of human embryos. In 1954 he was named full professor at the Central University of Madrid (Complutense current) enriching its collection (Orts-Llorca, 1984). In 1977 he was succeeded by Professor Juan Jiménez-Collado (1932) who incorporates his own collection and manages the creation of the Complutense Institute of Embryology. This is created in 1980, incorporating both seasons. Professor Jiménez-Collado is named Head of it. In 2002 Professor José-Vicente Sanz-Casado (1957) happens and your current Head.

Orts-Llorca F. 1984. Embriones y fetos humanos de diversas universidades españolas. Madrid: Editorial Universidad Complutense

A glance at Spanish embryology and teratology during the XX century through the academic life of Francisco Orts-Llorca (1905-1993)

Int J Dev Biol. 2009;53(8-10):1165-77. doi: 10.1387/ijdb.072492ja.

Aréchaga J1, Jiménez-Collado J, Ruano-Gil D. Author information

Abstract Francisco Ort-Llorca (1905-1993) was one of the most outstanding Spanish embryologists of the XX century. He was disciple of Henri Rouvire in Paris (France), Alfred Fischel in Vienna (Austria), Walther Vogt in Munich (Germany) and Pedro Ara in Madrid (Spain). From 1935, he was professor of Human Anatomy at the Faculty of Medicine of Cadiz, belonged then to the University of Seville (accidentally, in the University of Valencia, during the Spanish Civil War from 1936-1939) and, later on, at the Faculty of Medicine of Madrid (Complutense University) from 1954 to 1975. He was internationally recognized in anatomical sciences and stood out for his contributions to descriptive and experimental Embryology and Teratology, particularly in those aspects connected to the normal and pathological development of the heart and visual organs. PMID 19924623

PMID 4428951

Orts-Llorca F (1984) Embriones y fetos humanos de diversas Universidades españolas. Editorial Universidad Complutense.

Contact

Prof Luis Arráez Aybar

Prof Sanz-Casado

Departamento de Anatomía y Anatomía Patológica Comparada (Anatomía y Embriología)

http://www.ucm.es/dep-anatomiayembriologia

Department of Anatomy and Comparative Pathology (Anatomy and Embryology)

Universidad Complutense de Madrid

https://www.ucm.es