Talk:2012 Group Project 6

From Embryology

From the Course Coordinator

2012 Projects: Vision | Somatosensory | Taste | Olfaction | Abnormal Vision | Hearing


--Mark Hill 09:58, 18 September 2012 (EST) This is a recent review on vision. http://jcb.rupress.org/content/190/6/953.full JCB content allows reuse.

http://www.jove.com/video/3730/isolation-and-culture-of-human-fungiform-taste-papillae-cells

--Mark Hill 08:17, 16 August 2012 (EST) This small section at the top of your discussion page allows me to easily distribute information to all students looking at the group discussion page.

Please do not delete, edit or move the template {{Template:2012GroupDiscussion}} from the top of this page.

1. Search:

2. History

  • Embryology History Explore the rich history of sensory research. In particular look through the available images that may complement the text. Any of this material can be used, you should cite the original paper or textbook. Gray | 1921 Bailey and Miller

Hearing

Normal and Abnormal

Discussion Topics

Introduction

Not what hearing is but what we are going to talk about

History

Research Contribution

Adult Anatomy and Histology

<pubmed> 15495168 </pubmed>

<pubmed> 16015653 </pubmed>

<pubmed> 9433684 </pubmed>


Development

<pubmed> 6650859 </pubmed>

Outer Ear

Historic paper

<pubmed> 17104502 </pubmed>

<pubmed> 22296782 </pubmed>

<pubmed> 12874121 </pubmed>


Middle Ear

<pubmed> 18803631 </pubmed>

<pubmed> 21196256 </pubmed>

<pubmed> 14973294 </pubmed>

<pubmed> 11237469 </pubmed>

<pubmed> 16600992 </pubmed>


Inner Ear

(can include balance organs as well) cochlea and semi circular canals and the physiological function - how hearing works

Some papers to start with:

<pubmed>15319325</pubmed>

<pubmed>17891709</pubmed>

<pubmed>10887092</pubmed>

<pubmed>19247974</pubmed>

Abnormal Hearing

Just putting my articles in here so I can refer to them at a later date - will change the referencing when I have structured my points better


Genetic defects:

1. GJB2 Gene (accounting for 50% of non syndromic hearing loss)

Environmental

1. Drugs: Hearing, Speech, Language, and Vestibular Disorders in the Fetal Alcohol Syndrome: A Literature Review. Michael W. Church and James A. Kaltenbach, Alcoholism: Clinical and experimental review. Vol. 21, No. 3, May 1997 PMID: 9161611


2. Infections: Congenital Rubella Deafness: A preventable disease. C. S Peckham, J. M Martin, W. C Marshall, J. A Dudgeon, The Lancet, February 3, 1979 PMID: 84910

|Deafness and Hereditary Hearing Loss Overview

Etiological diagnosis in the hearing impaired newborn: Proposal of a flow chart. De Leenheer, E.M.R. ; Janssens, S. ; Padalko, E. ; Loose, D. ; Leroy, B.P. ; Dhooge, I.J. International Journal of Pediatric Otorhinolaryngology, 2011, Vol.75(1), pp.27-32

Congenital cytomegalovirus (CMV) infection as a cause of permanent bilateral hearing loss: A quantitative assessment. Journal of clinical virology [1386-6532] Grosse, Scott yr:2008 vol:41 iss:2 pg:57 -62

Congenital Infections. JF Bale. Neurol Clin. 2002 Nov;20(4):1039-60, vii. PMID: 12616680

Related to both middle and inner ear (so we can link the technologies to this)

Technologies to detect

Any technologies (like pre-testing) that identify any problems with hearing development

Technologies to overcome the problems

(hearing aids, cochlear transplants, etc)

Current Research

Glossary

References


Allocated subheadings

J: adult anatomy, outer and middle ear development

M: Inner ear

P: History and Technologies

B: Abnormal Hearing


Our Thoughts - put new comment at the top please

Hey B.! That sounds good :) Speak t you tomorrow! M. --Z3333865 13:22, 27 August 2012 (EST)


Hi!

In regards to my abnormalities (we can all discuss further this week), I will be focussing mainly on the gene GJB2 (which accounts for 50% of non syndromic hearing) and then for acquired hearing (organisms), I will focus mainly on what is known as "TORCH" organisms (i.e., toxoplasmosis, rubella, cytomegalic virus, and herpes) and go into details in them and then as M said before, just list the other in a table.

Thanks, B. --Z3292017 17:45, 26 August 2012 (EST)


Hey!

In regards to the hearing abnormalities, yes I would do the most common ones. It will be way too much otherwise! Just name the other abnormalities for now - depending on how long your section is we will include them or leave out. At the end of your section we can also put a table down with a summary of the common ones you explained in detail before :)

M. --Z3333865 13:07, 26 August 2012 (EST)


Hey guys,

Sorry I haven't been communicating via the discussion page, I've been sick in bed with a virus for the past week and half! Anyway, as I am focussing on the hearing abnormalities, I just wanted to clarify some things with you all. Firstly, there are A LOT of genetic disorder which contribute to hearing loss so I was thinking I would group them and would write in depth into the most common ones and then a brief description or just name the others. I'm currently compiling some research papers, so I will most likely get to writing some points on this page tomorrow.

Let me know if you have any suggestiosn etc and if I find any other articles in my research I will send them through! --Z3292017 18:44, 25 August 2012 (EST)


Hey all!

For this week, please find some good papers relating to your section - both primary and secondary - and start reading them. It will take some time to get all the info together and to also make it look good with pictures etc. So the sooner we start the easier it will be in the long-run!!

--Z3333865 21:00, 18 August 2012 (EST)


Hey everyone!

I guess if we end up doing the sensory topic and focus on the ear we can come up with some headings that we might want to use in our project.

This is the link to our lecture on the ear

I guess one way of doing this would be to divide it into inner, middle and outer ear and talk about the development of each. I guess we could include the progressive development over the weeks including cellular, molecular and morphological changes. We can also describe the developed ear, any genetic mutations or incorrect signal pathway that cause any defects. Then one part of it can be current research and any past research or noble prizes.

Cheers!

--Z3333794 11:31, 9 August 2012 (EST)


Hey all!

So we have to decide between normal development or abnormal development. Normal development can have headings as mentioned above, apart from the genetic mutations and defects. When focussing on abnormal development of the ear we can look at those mutations and defects. We can also look at technology such as hearing aids and the cochlear implant.

Please put down your preference! I really dont care.. but I think that if we have to discuss development it will be easiest to look at normal development.

--Z3333865 13:06, 14 August 2012 (EST)