Neutrophil extracellular trap Movie
Embryology - 4 Dec 2023 ![]() ![]() ![]() |
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Adult Mouse Neutrophil Extracellular Trap
<html5media height="450" width="592">File:Neutrophil extracellular trap 01.mp4</html5media> |
In vivo intracellular imaging demonstrates PMNs with normal, diffuse and absent nuclei during a Gram-positive skin infection. Normal nuclei are easily distinguished by their distinct multilobar morphology.
Anuclear PMNs are alive and continue to migrate. Examples are demonstrated of anuclear PMNs engorged with GFP-staphylococcus as well as anuclear PMNs devoid of bacteria. A PMN with an abnormal diffuse nucleus is highlighted for its multiple and erratic pseudopod formation and hyperpolarization. NETs are visualized within the area of anuclear PMNs. (text from Supplementary video legend) |
Reference
<pubmed>23700386</pubmed>| PLoS Biol. | PLoS Biol. Immunobiology Collection
Copyright
Reprinted by permission from Macmillan Publishers Ltd: Nat Med. (2012 Sep;18(9):1386-93.), copyright (2012)
Original video altered in size and labelling. 592 × 408
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Cite this page: Hill, M.A. (2023, December 4) Embryology Neutrophil extracellular trap Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neutrophil_extracellular_trap_Movie
- © Dr Mark Hill 2023, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G