Immune System - Abnormalities

Embryology - 26 Apr 2024 Expand to Translate
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Introduction

Lymphatic vessel development^[1]

Developing Human Thymus (stage 22)

Historic Embryology
1909 Lymph glands \| 1912 Development of the Lymphatic System \| 1918 Gray's Lymphatic Images \| 1916 Pig Lymphatics \| 1919 Chicken Lymphatic \| 1921 Spleen \| 1922 Pig Stomach Lymphatics \| 1932 Cat Pharyngeal Tonsil \| Historic Disclaimer

Tie1 is required for lymphatic valve and collecting vessel development^[2] "Tie1 is a receptor tyrosine kinase with broad expression in embryonic endothelium. Reduction of Tie1 levels in mouse embryos with a hypomorphic Tie1 allele resulted in abnormal lymphatic patterning and architecture, decreased lymphatic draining efficiency, and ultimately, embryonic demise. ... Our findings reveal a fundamental role for Tie signaling during lymphatic vessel remodeling and valve morphogenesis and implicate it as a candidate gene involved in primary lymphedema."

More recent papers
This table allows an automated computer search of the external PubMed database using the listed "Search term" text link. This search now requires a manual link as the original PubMed extension has been disabled. The displayed list of references do not reflect any editorial selection of material based on content or relevance. References also appear on this list based upon the date of the actual page viewing. References listed on the rest of the content page and the associated discussion page (listed under the publication year sub-headings) do include some editorial selection based upon both relevance and availability. More? References \| Discussion Page \| Journal Searches \| 2019 References \| 2020 References Search term: Immune System Abnormalities <pubmed limit=5>Immune System Abnormalities</pubmed>

Cite this page: Hill, M.A. (2024, April 26) Embryology Immune System - Abnormalities. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Immune_System_-_Abnormalities