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Zebrafish Epibrachial Placode Model

  • Before 12 hpf - Fgf3 and Fgf8 specify cells of the posterior placodal area that will give rise to the otic and EB placodes.
  • Between 14 and 22 hpf - Fgf10a, expressed by the anterior lateral line precursors and the forming otic vesicle, and Fgf3, expressed by the endoderm, are required for EB placode development by promoting the expression of Pax2a and Sox3 in a subset of cells of the Foxi1+ placodal competent ectoderm.
  • By 24 hpf - EB placodes are fully developed.


Abbreviations: NT, neural tube; MHB, midbrain hindbrain boundry; f, facial placode; ov, otic vesicle; All, anterior lateral line; g+v, glossopharyngeal/vagal placed.


Links: Placodes | Zebrafish Development

Reference

<pubmed>24358375</pubmed>| PLoS One.

Copyright

© 2013 McCarroll, Nechiporuk. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Figure 6. doi:10.1371/journal.pone.0085087.g006 Journal.pone.0085087.g006.jpg

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current00:32, 27 December 2013Thumbnail for version as of 00:32, 27 December 2013800 × 575 (82 KB)Z8600021 (talk | contribs)==Zebrafish Epibrachial Placode Model== Before 12 hpf, Fgf3 and Fgf8 specify cells of the posterior placodal area that will give rise to the otic and EB placodes. Shortly after, between 14 and 22 hpf, Fgf10a, expressed by the anterior lateral line pre...

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