File:Trophoblast hCG function.jpg

Trophoblast hCG function

Villous placental tissue, cytotrophoblast and syncytiotrophoblast cells, and regular hCG and hyperglycosylated hCG function.

Panel A - illustrated blastocyst implantation and engulfment and trophoblast invasion at 3–5 weeks of gestation. Arrows illustrates the biological functions of regular hCG and hyperglycosylated hCG. Mononuclear cells are cytotrophoblast cells, cells with multiple nuclei (black circles) represen syncytiotrophoblast cells.

Panel B - villous trophoblast formation and function are illustrated at 6–8 weeks of gestation. Figure illustrates villous trophoblast (anchoring villus and floating villus) growth 5 to 10 weeks of gestation, and invasion of the decidua and myometrium in establishing hemochorial placentation.

Panel C - illustrates functional hemochorial placentation in floating villus at 10–12 weeks of gestation after invasion is complete. Cells with varying numbers of multiple nuclei (black circles) represent villous syncytiotrophoblast (VSyn), mononuclear cells are villous cytotrophoblast (VCyto) and extravillous invasive cytotrophoblast (EVICyto). Arrows shows biological actions of regular hCG and hyperglycosylated hCG.

Reference

<pubmed>19171054</pubmed>| PMC2649930 | Reprod Biol Endocrinol.

Reprod Biol Endocrinol. 2009; 7: 8. Published online 2009 January 26. doi: 10.1186/1477-7827-7-8.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2009 Cole; licensee BioMed Central Ltd.