File:Thyroid signaling - endocrine-disrupting chemicals.jpg
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Thyroid Signaling Pathway and endocrine-disrupting chemicals
Abbreviations: NIS, sodium iodide symporters; TRH, thyroid-releasing hormone; TSH, thyroid-stimulating hormone; T4, thyroxine; T3, triiodothyronine.
| Groups of chemicals | Level of Acton | 
|
|---|---|---|
| polychlorinated biphenyl (PCB) and polychlorinated dibenzodioxins (PCDD) | 5, 7 | |
| polybrominated diphenyl ethers (PBDEs) | 5, 6, 7, 8 | |
| pesticides | 4, 5, 7 | |
| perfluoroalkyl substances (PFASs) | 5, 6; NIS: 3 | |
| bisphenol A (BPA) | 2, 7 | |
| phthalates | 1, 2, 5, 8. | |
| Table Data[1] Links: thyroid | chemicals | endocrine abnormalities | ||
- Links: thyroid | endocrine abnormalities
Reference
Ghassabian A & Trasande L. (2018). Disruption in Thyroid Signaling Pathway: A Mechanism for the Effect of Endocrine-Disrupting Chemicals on Child Neurodevelopment. Front Endocrinol (Lausanne) , 9, 204. PMID: 29760680 DOI.
Copyright
© 2018 Ghassabian and Trasande. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Figure 1. Image of thyroid: by P. J. Witt, AU from the Noun Project, Creative Commons.
Cite this page: Hill, M.A. (2024, April 27) Embryology Thyroid signaling - endocrine-disrupting chemicals.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Thyroid_signaling_-_endocrine-disrupting_chemicals.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 16:57, 21 May 2018 | | 800 × 889 (74 KB) | Z8600021 (talk | contribs) | Figure 1. Thyroid signaling pathway and endocrine-disrupting chemicals. Groups of chemicals act at: PCB and PCDD: 5, 7; PBDEs: 5, 6, 7, 8; pesticides: 4, 5, 7; PFASs: 5, 6; NIS: 3; BPA: 2, 7; phthalates: 1, 2, 5, 8. Abbreviations: BPA, bisphenol A; NIS... |
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