File:Placenta Hofbauer cells 01.jpg

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Placenta Hofbauer Cells

  • human villous macrophages
  • highly vacuolated cells
  • located the core of placental villi and cord
  • macrophages with micropinocytotic activity and phagocytosis ability
  • possible paracrine role for early stages of placental vasculogenesis


Tissue from a representative first miscarriage, 9th week of gestation (GA week 9; approx. post-fertilization age week 7).

Paraffin serial sections. A subpopulation of Hofbauer cells residing in the villous stroma, identified by are positive for CD100 (panel a, red asterisks)

Bar = 60 µm.


Links: Hofbauer cells | placental villi

Reference

Lorenzi T, Turi A, Lorenzi M, Paolinelli F, Mancioli F, La Sala L, Morroni M, Ciarmela P, Mantovani A, Tranquilli AL, Castellucci M & Marzioni D. (2012). Placental expression of CD100, CD72 and CD45 is dysregulated in human miscarriage. PLoS ONE , 7, e35232. PMID: 22606231 DOI.


Copyright=

© 2012 Lorenzi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Figure 2. panel A resized, contrast adjusted and inset enlargement added. doi:10.1371/journal.pone.0035232.g002 Journal.pone.0035232.g002.jpg


Cite this page: Hill, M.A. (2024, April 17) Embryology Placenta Hofbauer cells 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Placenta_Hofbauer_cells_01.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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Date/TimeThumbnailDimensionsUserComment
current13:51, 20 November 2012Thumbnail for version as of 13:51, 20 November 2012934 × 700 (156 KB)Z8600021 (talk | contribs)
13:35, 20 November 2012Thumbnail for version as of 13:35, 20 November 2012934 × 700 (153 KB)Z8600021 (talk | contribs)==Placenta Hofbauer cells== Figure 2. Tissue from a representative first miscarriage, 9th week of gestation. Paraffin serial sections. A subpopulation of Hofbauer cells residing in the villous stroma, identified by are positive for CD100 (panel a, red a

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