File:Mouse tongue Pax9 expression 02.jpg

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Expression patterns of Pax9 in different taste papillae of the embryonic mouse tongue

Pax9 immunostaining of taste papillae during development on cross sections (C–F; K–N) and horizontal sections of the tongue (G–J).

  • C–F Pax9 is expressed in the epithelium during CVP morphogenesis and is down-regulated in some regions of the trenches at E18.5 (arrowhead in F).
  • G–J In addition to the epithelium, Pax9 is also expressed in the mesenchyme during FOP development, while reduced Pax9 levels were observed in the trenches at E18.5 (arrowhead in J).
  • K–N In the anterior part of the tongue Pax9 is expressed in the FUP epithelium and in filiform papillae (FIP). Note that the expression is very weak or absent in the taste placodes (arrowheads). Scale bars: 200 µm in B; 50 µm in other panels.

Taste Links: Image - Mouse E13.5 tongue Pax9 | Image - Mouse E13.5-18.5 tongue Pax9 | Image - Mouse tongue Pax9 | taste | PAX | tongue | mouse


Kist R, Watson M, Crosier M, Robinson M, Fuchs J, Reichelt J & Peters H. (2014). The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells. PLoS Genet. , 10, e1004709. PMID: 25299669 DOI.


© 2014 Kist et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Figure 1. doi:10.1371/journal.pgen.1004709.g001 Cropped, Resized and relabelled from original.

Cite this page: Hill, M.A. (2024, April 13) Embryology Mouse tongue Pax9 expression 02.jpg. Retrieved from

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current11:15, 12 February 2015Thumbnail for version as of 11:15, 12 February 20151,200 × 833 (299 KB)Z8600021 (talk | contribs)==Expression patterns of Pax9 in different taste papillae of the embryonic mouse tongue== '''A.''' Drawing showing the localization of the circumvallate papilla (CVP), foliate papillae (FOP), and fungiform papillae (FUP) in the mouse tongue. '''B.''...

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