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Mouse Respiratory Development Fibroblast Growth Factor Signaling

Signaling (Fgf10-Fgfr2b) in lung bud morphogenesis.

A. Lung budding results from mesodermal induction of Fgf10 and activation of Fgfr2b signaling in the Titf1-expressing endoderm at the prospective lung field.

B. Fgf10 and Fgfr2b expression in the E9.5 lung primordium by in situ hybridization. (Fgf10, mesoderm associated with emerging lung buds; Fgfr2b, lung endoderm).

C. Diagram representing known or putative regulators of Fgf10 expression in the developing lung; see text for details and references. Modified from Cardoso and Lu (2006).

Links: Fibroblast Growth Factor | Respiratory System Development

Reference

<pubmed>20614584</pubmed>

StemBook - Specification and patterning of the respiratory system

Copyright

© 2008 Wellington V. Cardoso and Darrell N. Kotton. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Original file name: Figure 4. Cardoso04.jpg http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=stembook&part=specificationandpatterning&rendertype=figure&id=specificationandpatterning.F4



Cite this page: Hill, M.A. (2024, June 21) Embryology Mouse- respiratory development 04.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Mouse-_respiratory_development_04.jpg

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current06:53, 11 November 2010Thumbnail for version as of 06:53, 11 November 2010800 × 728 (73 KB)S8600021 (talk | contribs)==Mouse Respiratory Development Fibroblast Growth Factor Signaling== Signaling (Fgf10-Fgfr2b) in lung bud morphogenesis. A. Lung budding results from mesodermal induction of Fgf10 and activation of Fgfr2b signaling in the Titf1-expressing endoderm at th