File:Limb induction-initiation signal 01.jpg: Difference between revisions

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Molecular Mechanisms of Limb Bud Formation

Nishimoto et al. reveal the regulatory network including retinoic acid (RA), b-catenin pathway, and Tbx genes controlling the early steps of limb formation. This study demonstrates the shared role of RA in forelimb and hindlimb and an evolutionarily conserved role of the b-catenin pathway in limb induction.

Reference

Nishimoto S, Wilde SM, Wood S & Logan MP. (2015). RA Acts in a Coherent Feed-Forward Mechanism with Tbx5 to Control Limb Bud Induction and Initiation. Cell Rep , 12, 879-91. PMID: 26212321 DOI.

Copyright

Cite this page: Hill, M.A. (2024, May 18) Embryology Limb induction-initiation signal 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Limb_induction-initiation_signal_01.jpg

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 ==Molecular Mechanisms of Limb Bud Formation==
+Nishimoto et al. reveal the regulatory network including {{retinoic acid}} (RA), b-catenin pathway, and Tbx genes controlling the early steps of limb formation. This study demonstrates the shared role of RA in forelimb and hindlimb and an evolutionarily conserved role of the b-catenin pathway in limb induction.
+:[[Musculoskeletal System - Limb Development|'''Links''']]: [[:File:Limb induction-initiation signal 01.jpg|image - summary]] | [[:File:Limb induction-initiation signal 02.jpg|image - signal interaction]] | [[Developmental Signals - Retinoic acid|Retinoic acid]] | [[Developmental Signals - Tbx|Tbx]] | [[Developmental Signals - Fibroblast Growth Factor|FGF]] | [[Musculoskeletal System - Limb Development|Limb Development]]
 ===Reference===
+{{#pmid:26212321}}
 ====Copyright====
+Copyright © 2015 The Authors
+This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
 {{Footer}}
+[[Category:Limb]][[Category:Cartoon]][[Category:FGF]][[Category:Retinoic acid]][[Category:Tbx]]
-[[Category:Limb]][[Category:RA]][[Category:TBX]][[Category:Cartoon]]