File:Hypothalamus model 01.jpg
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Hypothalamus Model
Apparent sources of patterning diffusible morphogens that may have effects on the hypothalamus.
Anterior neural ridge (ANR; yellow), which releases FGF8 is in fact a part of the Template:Roof plate (dorsalizing influence), rather than a source of AP effects.
in contrast, the retromamillary and mamillary Template:Floor plate (dark blue associated to RM and M) releases SHH (ventralizing influence; note Shh secondarily also is expressed throughout the basal plate, and is later downregulated at the Tu area).
The acroterminal midline as a source of AP patterning effects. Recent observations show Fgf18 expression within the postulated alar acroterminal organizer (fuchsia-labeled) and Fgf8 and Fgf10 expression within the postulated basal acroterminal organizer (green-labeled). There also are bilateral spots of Fgf8 expression at the optic stalks (not shown). (text modified from original figure legend)
See also Image - Brain stem subdivisions
- Links: hypothalamus | midbrain | SHH | Fgf
Reference
Puelles L & Rubenstein JL. (2015). A new scenario of hypothalamic organization: rationale of new hypotheses introduced in the updated prosomeric model. Front Neuroanat , 9, 27. PMID: 25852489 DOI.
Copyright
201 5 Puelles and Rubenstein. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Cite this page: Hill, M.A. (2024, April 27) Embryology Hypothalamus model 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Hypothalamus_model_01.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 14:09, 25 February 2020 | | 1,089 × 796 (119 KB) | Z8600021 (talk | contribs) | ==Hypothalamus Model== Apparent sources of patterning diffusible morphogens that may have effects on the hypothalamus. Anterior neural ridge (ANR; yellow), which releases {{FGF}}8 is in fact a part of the roof plate (dorsalizing influence), rather than a source of AP effects. in contrast, the retromamillary and mamillary floor plate (dark blue associated to RM and M) releases {{SHH}} (ventralizing influence; note Shh secondarily also is expressed throughout the basal plate, and is later d... |
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