File:Human female fibroblast line (47,XXX) XIST expression.jpg

Human Female Fibroblast line (47,XXX) XIST Expression

XIST expression in two cell nuclei using RNA FISH probes for the human XIST RNA (green) in the human female fibroblast line GM04626 (karyotype: 47,XXX). As there are 3 copies of the X chromosome in each cell, there are 2 inactive X chromosomes as shown by Xist staining.

Links: Molecular Development - X Inactivation

Original file name: Figure 1. journal.pone.0010787.g001.jpg (Image extracted from panel C of the complete original figure and slightly increased in size)

doi:10.1371/journal.pone.0010787.g001

Reference

Thorogood NP & Brown CJ. (2010). Active chromatin marks are retained on X chromosomes lacking gene or repeat silencing despite XIST/Xist expression in somatic cell hybrids. PLoS ONE , 5, e10787. PMID: 20520737 DOI.

Copyright

© 2010 Thorogood, Brown. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cite this page: Hill, M.A. (2024, April 27) Embryology Human female fibroblast line (47,XXX) XIST expression.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Human_female_fibroblast_line_(47,XXX)_XIST_expression.jpg

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