File:Human embryo olfactory 01.jpg

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Development of the Human Olfactory System (Carnegie Stage 15, 17 and 20)

(A-F) Development of the olfactory epithelium (OE) and vomeronasal epithelium (VNE).

  • A The arrow points to the invaginated OP in front of the telencephalon.
  • B The nasal cavities have developed and the presumptive VNO is first delineated (arrows).
  • C A transverse section of a VNO shows a small tube lined with a pseudostratified epithelium.
  • D, E The entry of the VNO (arrow) is lined with a respiratory epithelium; calretinin-positive cells are present in the VNE and in the cell-stream leaving the VNO.
  • F Many calretinin-positive cells are present in the OE.
  • G-I Development of the OB. (G) Higher magnification of A shows the basal telencephalon consists of a thick proliferating ventricular zone and a narrow marginal zone.
  • H ICBP immunostaining (purple nuclei) shows that the MZ has developed.
  • I A low magnification of a coronal section at CS 20 shows that the olfactory fibres have reached the telencephalon and form a distinct layer at the surface of the developing OB; OBs are present with a peripheral fibre layer, a differentiating layer and a ventricular layer.


Abbreviations: (cal) calretinin immunostaining, (CS) Carnegie stage, (HE) hematoxylin-eosin staining, (MZ) marginal zone, (OB) olfactory bulb, (OP) olfactory placode, (Tel) telencephalon.


Links: Smell Development | Carnegie stage 15 | Carnegie stage 17 | Carnegie stage 20

Reference

<pubmed>26270645</pubmed>

Copyright

© 2015 Antal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Fig 1. doi:10.1371/journal.pone.0135710.g001 Journal.pone.0135710.g001.jpg



Cite this page: Hill, M.A. (2024, April 27) Embryology Human embryo olfactory 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Human_embryo_olfactory_01.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current15:20, 18 August 2015Thumbnail for version as of 15:20, 18 August 20152,044 × 1,552 (986 KB)Z8600021 (talk | contribs)==Development of the Human Olfactory System (Carnegie Stage 15, 17 and 20)== (A-F) Development of the olfactory epithelium (OE) and vomeronasal epithelium (VNE). * A) The arrow points to the invaginated OP in front of the telencephalon. (B) The na...

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