File:Hair follicle development.jpg
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Organization of the epidermis.
Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The schematic shows the organization of keratinocytes in the IFE, as proposed by the stem/TA cell hypothesis. The basal layer comprises stem cells (S, blue), transit amplifying cells (TA, dark green), and post-mitotic basal cells (red), which migrate out of the basal layer as they differentiate (arrows).
Projected Z-stack confocal images of IFE wholemounts from AhcreERT R26EYFP/wt mice viewed from the basal surface at the times shown following induction. Yellow, EYFP; blue, DAPI nuclear stain. Scale bar, 20 microns.
Original file name: Nature05574-f1.2.jpg
Reference
<pubmed>17330052</pubmed>
Reprinted by permission from Macmillan Publishers Ltd: Nature. 2007 Mar 8;446(7132):185-9, copyright (2007)
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 00:37, 22 April 2010 | | 800 × 663 (191 KB) | S8600021 (talk | contribs) | Organization of the epidermis. Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The s |
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