File:Fly WT dorsal view head thorax SEM.jpg
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Fly Wild-type (WT) Head and Thorax (dorsal view SEM)
- Links: Image - WT dorsal view head thorax SEM | Image - Hippo-type dorsal view head thorax SEM | Fly Development | Developmental Signals - Hippo | Scanning Electron Microscopy
Reference
<pubmed>24336504</pubmed>| Nat Rev Drug Discov.
Copyright
Reprinted by permission from Macmillan Publishers Ltd: Nature Reviews Drug Discovery (Randy Johnson, Georg Halder The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment. Nat Rev Drug Discov: 2014, 13(1);63-79), copyright (2015)
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current | 10:51, 11 June 2015 | 555 × 796 (95 KB) | Z8600021 (talk | contribs) | ==The Hippo Pathway and its mode of action== * '''A''' - When the Hippo pathway is ON, MST1/2 phosphorylate SAV1 and together they phosphorylate and activate MOB1A/B and LATS1/2, which then phosphorylate YAP and TAZ. Phosphorylated YAP and TAZ are se... |
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