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Evolutionary history of the Fgf gene family

Fgf13-like is an ancestral gene of the Fgf family. Fgf4-like is an ancestral gene of the canonical Fgf family. Fgf4-like was generated from Fgf13-like by gene duplication. Fgf15/19-like, an ancestral gene of the hormone-like Fgf subfamily, was generated from Fgf4-like by local gene duplication early in vertebrate evolution. Later, Fgf15/19, Fgf21, and Fgf23 were generated by two large-scale genome duplication events during the evolution of early vertebrates

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This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Itoh N. Department of Genetic Biochemistry, Kyoto University Graduate School of Pharmaceutical Sciences, Kyoto, Japan. itohnobu@pharm.kyoto-u.ac.jp http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948652

Cell Tissue Res. 2010 October; 342(1): 1–11. Published online 2010 August 24. doi: 10.1007/s00441-010-1024-2. Original file name: Fig. 1 441_2010_1024_Fig1_HTML.jpg http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948652/figure/Fig1/

Cite this page: Hill, M.A. (2024, May 25) Embryology Fgf gene family evolution.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Fgf_gene_family_evolution.jpg

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	Date/Time	Thumbnail	Dimensions	User	Comment
current	09:16, 7 October 2015		759 × 400 (49 KB)	Z8600021 (talk \| contribs)	increase size add PMID 20730630
	23:31, 3 May 2011		488 × 257 (51 KB)	S8600021 (talk \| contribs)	==Evolutionary history of the Fgf gene family== Fgf13-like is an ancestral gene of the Fgf family. Fgf4-like is an ancestral gene of the canonical Fgf family. Fgf4-like was generated from Fgf13-like by gene duplication. Fgf15/19-like, an ancestral gene o

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Developmental Signals - Fibroblast Growth Factor

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 Fgf13-like is an ancestral gene of the Fgf family. Fgf4-like is an ancestral gene of the canonical Fgf family. Fgf4-like was generated from Fgf13-like by gene duplication. Fgf15/19-like, an ancestral gene of the hormone-like Fgf subfamily, was generated from Fgf4-like by local gene duplication early in vertebrate evolution. Later, Fgf15/19, Fgf21, and Fgf23 were generated by two large-scale genome duplication events during the evolution of early vertebrates
-Original file name: Fig. 1 441_2010_1024_Fig1_HTML.jpg http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948652/figure/Fig1/
-==Reference==
+===Reference===
+<pubmed>20730630</pubmed>
-Cell Tissue Res. 2010 Oct;342(1):1-11. Epub 2010 Aug 24.
+====Copyright====
-Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease.
+© Itoh N. 2010
-Itoh N.Department of Genetic Biochemistry, Kyoto University Graduate School of Pharmaceutical Sciences, Kyoto, Japan. itohnobu@pharm.kyoto-u.ac.jp http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948652
-Cell Tissue Res. 2010 October; 342(1): 1–11.
+This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
-Published online 2010 August 24. doi: 10.1007/s00441-010-1024-2.
-Copyright © The Author(s) 2010
+Itoh N. Department of Genetic Biochemistry, Kyoto University Graduate School of Pharmaceutical Sciences, Kyoto, Japan. itohnobu@pharm.kyoto-u.ac.jp http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948652
-This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
+Cell Tissue Res. 2010 October; 342(1): 1–11. Published online 2010 August 24. doi: 10.1007/s00441-010-1024-2.
+Original file name: Fig. 1 441_2010_1024_Fig1_HTML.jpg http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948652/figure/Fig1/
+{{Footer}}