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DNA Sequencing Methods

How previous generation DNA-sequencing systems work.

(A) A modern implementation of Sanger sequencing is shown to illustrate differential labeling and use of terminator chemistry followed by size separation to resolve the sequence.

(B) The Illumina sequencing process is shown to illustrate the wash-and-scan paradigm common to second-generation DNA-sequencing technologies.

Original File name: Figure 1. http://hmg.oxfordjournals.org/content/19/R2/R227/F1.expansion.html

Reference

Schadt EE, Turner S & Kasarskis A. (2010). A window into third-generation sequencing. Hum. Mol. Genet. , 19, R227-40. PMID: 20858600 DOI.

Copyright

© The Author 2010. Published by Oxford University Press

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cite this page: Hill, M.A. (2024, April 15) Embryology DNA sequencing methods.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:DNA_sequencing_methods.jpg

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current09:47, 20 December 2010Thumbnail for version as of 09:47, 20 December 2010806 × 1,000 (104 KB)S8600021 (talk | contribs)==DNA Sequencing Methods== How previous generation DNA-sequencing systems work. (A) A modern implementation of Sanger sequencing is shown to illustrate differential labeling and use of terminator chemistry followed by size separation to resolve the seq

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