File:Blood-brain barrier EM01.jpg

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Mouse Blood-brain barrier (EM)

Fig. 11 Regions of overlap between neighboring endothelial cells, illustrating range of variation in structure of the intercellular cleft. In Fig. 11, the cleft is obliterated by a tight junction (arrow) extending throughout most of its length. The region of the intercellular cleft indicated by the arrow in Fig. 11 is shown in inset at higher magnification to illustrate that the total width of the tight junc- tion (between arrows at right) is less than twice the width of the adjacent plasma membrane (between arrows at left). Fig. 12 Astrocytic end feet (A) lying between a myelinated axon and the basement lamina of the vascular endothelium. A cleft between the astrocytic end feet extends from the basement lamina to a perivascular myelinated axon and appears open except near the blood vessel where it is invaded by some basement lamina material.
Normal mouse; uranyl acetate block stain. Fig. 11, X 170,000. Fig. 11 inset, X 420,000. Normal mouse; uranyl acetate block stain. X 150,000.


Links: Blood-Brain Barrier | Neural - Vascular Development | Blood-brain barrier cartoon

Reference

Reese TS & Karnovsky MJ. (1967). Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. , 34, 207-17. PMID: 6033532


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Cite this page: Hill, M.A. (2024, March 3) Embryology Blood-brain barrier EM01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Blood-brain_barrier_EM01.jpg

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G

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current12:31, 29 May 2017Thumbnail for version as of 12:31, 29 May 20171,656 × 810 (250 KB)Z8600021 (talk | contribs)
12:30, 29 May 2017Thumbnail for version as of 12:30, 29 May 20171,656 × 810 (223 KB)Z8600021 (talk | contribs)FIGURE 11 Regions of overlap between neighboring endothelial cells, illustrating range of variation in structure of the intercellular cleft. In Fig. 11, the cleft is obliterated by a tight junction (arrow) extending throughout most of its length. The...

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