BGDB Sexual Differentiation - Early Embryo: Difference between revisions
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'''Next observe the changes occuring in the hindgut region (yellow) ending in the embryo at the cloaca.''' | '''Next observe the changes occuring in the hindgut region (yellow) ending in the embryo at the cloaca.''' | ||
* The posterior portion (nearest the mesonephros) remains as the gastrointestinal tract. | * The posterior portion (nearest the mesonephros) remains as the gastrointestinal tract hindgut forming the '''rectum'''. | ||
* The anterior portion (extends into the connecting stalk as the allantois) | * The anterior portion (extends into the connecting stalk as the '''allantois''') | ||
** becomes separated from the hindgut and forms the primordia of the urinary bladder | ** becomes separated from the hindgut and forms the '''urogenital sinus''', primordia of the urinary bladder. | ||
** | ** The two '''mesonephric ducts''' initially open into the urogenital sinus. | ||
|} | |} | ||
Revision as of 15:06, 2 June 2011
Practical 12: Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | 2011 Audio |
Week 4 to 5
<wikiflv width="560" height="588" autoplay="true" position="left">Stage13_GITlarge.flv|File:Stage13-GIT-icon.jpg</wikiflv> |
Begin by observing the internal structure of the embryo at the end of week 4 and the beginning of week 5.
Colour code:
|
Mesonephros and Mesonephric Duct
E1-G4: Section passes dorsally to the mesonephros. Return to G4 and then follow the caudal route of the mesonephric duct into the sacral region.
E1L | E2L | E3L | E4L | E5L | E6L | E7L |
F1L | F2L | F3L | F4L | F5L | F6L | F7L |
G1L | G2L | G3L | G4L |
Kidney and Mesonephric Duct
<wikiflv width="356" height="500" autoplay="true" position="left">Urogenital_sinus_001.flv|File:Urogenital_sinus_001 icon.jpg</wikiflv> |
Now go back and observe the development of the intermediate mesoderm.
|
Primitive Urogenital Sinus
Gonad Development
Male Testis
Female Ovary
Gonadal Development Comparison
Now directly compare the development of the male and female gonad (click image to start, these may not be synchronised).
Gonad-icon.jpg</wikiflv> | Gonad-icon.jpg</wikiflv> |
Ovary | Testis |
Practical 12: Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | 2011 Audio |
Additional Information
The following figures are from a recent review of Sex determination and gonadal development in mammals.[1]
- Signaling in genital development
- Sex reversal in humans caused by abnormal X-Y exchange
- Mesonephric tubules in the 11.5 dpc mouse urogenital ridge
- Development and differentiation of the genital duct system
- The migratory pathway of primordial germ cells
- Structure of the early fetal testis
- Differentiation of pre-Sertoli cells into Sertoli cells
- Model for cell-autonomous and prostaglandin-mediated upregulation of Sox9 in pre-Sertoli cells
- Visualization of testicular cell types
- Ovary and follicle development and differentiation
- Postulated molecular pathway leading to the formation of the bipotential genital ridge
- Structure of mouse and human SRY protein
- Postulated interaction of molecular players involved in early testicular development
References
- ↑ <pubmed>17237341</pubmed>| Physiol. Rev.
Nussey S, Whitehead S. Endocrinology: An Integrated Approach. Oxford: BIOS Scientific Publishers; 2001. Chapter 6 The gonad
BGDB: Lecture - Gastrointestinal System | Practical - Gastrointestinal System | Lecture - Face and Ear | Practical - Face and Ear | Lecture - Endocrine | Lecture - Sexual Differentiation | Practical - Sexual Differentiation | Tutorial
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Cite this page: Hill, M.A. (2024, May 20) Embryology BGDB Sexual Differentiation - Early Embryo. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/BGDB_Sexual_Differentiation_-_Early_Embryo
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G