BGDB Sexual Differentiation - Early Embryo: Difference between revisions
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The following figures are from a recent review of Sex determination and gonadal development in mammals.<ref><pubmed>17237341</pubmed>| [http://physrev.physiology.org/content/87/1/1.long Physiol. Rev.]</ref> | The following figures are from a recent review of Sex determination and gonadal development in mammals.<ref><pubmed>17237341</pubmed>| [http://physrev.physiology.org/content/87/1/1.long Physiol. Rev.]</ref> | ||
# [http://physrev.physiology.org/content/87/1/1/F1.expansion.html Signaling in genital development] | # [http://physrev.physiology.org/content/87/1/1/F1.expansion.html Signaling in genital development] | ||
# [http://physrev.physiology.org/content/87/1/1/ | # [http://physrev.physiology.org/content/87/1/1/F2.expansion.html Sex reversal in humans caused by abnormal X-Y exchange] | ||
# [http://physrev.physiology.org/content/87/1/1/F6.expansion.html Structure of the early fetal testis] | |||
# [http://physrev.physiology.org/content/87/1/1/F7.expansion.html Mesonephric tubules in the 11.5 dpc mouse urogenital ridge] | # [http://physrev.physiology.org/content/87/1/1/F7.expansion.html Mesonephric tubules in the 11.5 dpc mouse urogenital ridge] | ||
# [http://physrev.physiology.org/content/87/1/1/F8.expansion.html Development and differentiation of the genital duct system] | # [http://physrev.physiology.org/content/87/1/1/F8.expansion.html Development and differentiation of the genital duct system] | ||
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# [http://physrev.physiology.org/content/87/1/1/F12.expansion.html Model for cell-autonomous and prostaglandin-mediated upregulation of Sox9 in pre-Sertoli cells] | # [http://physrev.physiology.org/content/87/1/1/F12.expansion.html Model for cell-autonomous and prostaglandin-mediated upregulation of Sox9 in pre-Sertoli cells] | ||
# [http://physrev.physiology.org/content/87/1/1/F13.expansion.html Visualization of testicular cell types] | # [http://physrev.physiology.org/content/87/1/1/F13.expansion.html Visualization of testicular cell types] | ||
# [http://physrev.physiology.org/content/87/1/1/F3.expansion.html Postulated molecular pathway leading to the formation of the bipotential genital ridge] | # [http://physrev.physiology.org/content/87/1/1/F3.expansion.html Postulated molecular pathway leading to the formation of the bipotential genital ridge] | ||
# [http://physrev.physiology.org/content/87/1/1/F4.expansion.html Structure of mouse and human SRY protein] | # [http://physrev.physiology.org/content/87/1/1/F4.expansion.html Structure of mouse and human SRY protein] |
Revision as of 11:30, 29 May 2012
Practical 12: Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | 2011 Audio |
Week 4 to 5
<wikiflv width="560" height="588" autoplay="true" position="left">Stage13_GITlarge.flv|File:Stage13-GIT-icon.jpg</wikiflv> |
Begin by observing the internal structure of the embryo at the end of week 4 and the beginning of week 5.
Colour code:
|
Mesonephros and Mesonephric Duct
Section 29-46: (E1-G4) Section passes dorsally to the mesonephros. Return to G4 and then follow the caudal route of the mesonephric duct into the sacral region.
29 (E1L) | 30 (E2L) | 31 (E3L) | 32 (E4L) | 33 (E5L) | 34 (E6L) | 35 (E7L) |
36 (F1L) | 37 (F2L) | 38 (F3L) | 39 (F4L) | 40 (F5L) | 41 (F6L) | 42 (F7L) |
43 (G1L) | 44 (G2L) | 45 (G3L) | 46 (G4L) |
Kidney and Mesonephric Duct
<wikiflv width="356" height="500" autoplay="true" position="left">Urogenital_sinus_001.flv|File:Urogenital_sinus_001 icon.jpg</wikiflv> |
Now go back and observe the development of the intermediate mesoderm.
|
Primitive Urogenital Sinus
Gonad Development
Male Testis
Female Ovary
Gonadal Development Comparison
Now directly compare the development of the male and female gonad (click image to start, these may not be synchronised).
Gonad-icon.jpg</wikiflv> | Gonad-icon.jpg</wikiflv> |
Ovary | Testis |
Practical 12: Sex Determination | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | 2011 Audio |
Additional Information
The following figures are from a recent review of Sex determination and gonadal development in mammals.[1]
- Signaling in genital development
- Sex reversal in humans caused by abnormal X-Y exchange
- Structure of the early fetal testis
- Mesonephric tubules in the 11.5 dpc mouse urogenital ridge
- Development and differentiation of the genital duct system
- The migratory pathway of primordial germ cells
- Structure of the early fetal testis
- Differentiation of pre-Sertoli cells into Sertoli cells
- Model for cell-autonomous and prostaglandin-mediated upregulation of Sox9 in pre-Sertoli cells
- Visualization of testicular cell types
- Postulated molecular pathway leading to the formation of the bipotential genital ridge
- Structure of mouse and human SRY protein
- Postulated interaction of molecular players involved in early testicular development
References
- ↑ <pubmed>17237341</pubmed>| Physiol. Rev.
Nussey S, Whitehead S. Endocrinology: An Integrated Approach. Oxford: BIOS Scientific Publishers; 2001. Chapter 6 The gonad
BGDB: Lecture - Gastrointestinal System | Practical - Gastrointestinal System | Lecture - Face and Ear | Practical - Face and Ear | Lecture - Endocrine | Lecture - Sexual Differentiation | Practical - Sexual Differentiation | Tutorial
Glossary Links
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Cite this page: Hill, M.A. (2024, April 26) Embryology BGDB Sexual Differentiation - Early Embryo. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/BGDB_Sexual_Differentiation_-_Early_Embryo
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G