Talk:Birth - Macrosomia

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Cite this page: Hill, M.A. (2026, October 1) Embryology Birth - Macrosomia. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Birth_-_Macrosomia

2010

Macrosomia: a new formula for optimized fetal weight estimation

Ultrasound Obstet Gynecol. 2010 Jan;35(1):42-7.

Hart NC, Hilbert A, Meurer B, Schrauder M, Schmid M, Siemer J, Voigt M, Schild RL. Source Department of Obstetrics and Gynecology, Diakonische Dienste Henriettenstiftung, Hannover, Germany. Erratum in Ultrasound Obstet Gynecol. 2011 Feb;37(2):254.

Abstract

OBJECTIVES: To develop and test a specific formula for estimating weight in the macrosomic fetus. METHODS: Ultrasound estimations of fetal weight were carried out within 1 week of delivery in 424 singleton fetuses with a birth weight of > or = 4000 g. Exclusion criteria were multiple pregnancy, intrauterine death and major structural or chromosomal anomalies. Stepwise regression modeling was used to derive a prediction formula with birth weight as the dependent variable and maternal booking weight and fetal biometric measurements as independent parameters. After a new formula for estimated fetal weight (EFW) had been developed in a formula-finding group (n = 284), it was compared with commonly used weight equations (evaluation group, n = 140). RESULTS: The new formula (log(e)EFW = 7.6377445039 + 0.0002951035 x maternal weight + 0.0003949464 x head circumference + 0.0005241529 x abdominal circumference + 0.0048698624 x femur length) proved to be superior to established equations, with the smallest mean error (mean +/- SD, -10 +/- 202 g), the smallest mean percentage error (mean +/- SD, -0.03 +/- 4.6%) and the lowest mean absolute percentage error (3.69 (range, 0.05-13.57)%) when studied in the evaluation group. With the new formula, 77.9% of estimates fell within +/- 5% of the actual weight at birth, 97.1% within +/- 10%, and 100% within +/- 15% and +/- 20%. CONCLUSIONS: The new formula allows better weight estimation in the macrosomic fetus. Comment in Ultrasound Obstet Gynecol. 2010 Apr;35(4):503-4; author reply 504-5.

PMID 20034003