File:Primordial germ cell DNA methylation 01.jpg

Primordial Germ Cell DNA Methylation

Nuclear distribution of H3K79me2 and H3K79me3 in fetal germ cells.

Female and male germ cells (FGC and MGC, respectively) and female somatic cells (SC) at 15.5 dpc were stained with the H3K79me2 and H3K79me3 antibodies as indicated and are shown in the different channels separately and in red-blue composite. (A) DAPI-stained chromocenters are excluded from H3K79me2 signals (open arrowheads). (B) DAPI-rich chromocenters colocalize with H3K79me3 signals (closed arrowheads). Other details are as in legend to Figure 1.

Figure 9. Journal.pone.0023848.g009.jpg

Reference

Abe M, Tsai SY, Jin S-G, Pfeifer GP, Szabó PE (2011) Sex-Specific Dynamics of Global Chromatin Changes in Fetal Mouse Germ Cells. PLoS ONE 6(8): e23848. doi:10.1371/journal.pone.0023848

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0023848

© 2011 Abe et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.