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Mouse Wnt/beta-Catenin Signaling
The development of a novel mouse transgenic line allows the study of Wnt signaling activity in living embryos at single-cell resolution. Transgenic mice express a reporter comprising GFP fused to human histone H2B under the control of Wnt/ß-catenin signaling pathway response elements. Expression of GFP mimics canonical Wnt/ß -catenin signaling activity. At embryonic day 10.5, as shown by live imaging, GFP expression is observed in the neural tube, somites, heart, nasal and pharyngeal region (GFP; green)
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Reference
<pubmed>21176145</pubmed>| BMC Dev Biol.
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| current | 15:07, 28 December 2010 | | 600 × 450 (156 KB) | S8600021 (talk | contribs) | ==Mouse Wnt/beta-Catenin Signaling== The development of a novel mouse transgenic line allows the study of Wnt signaling activity in living embryos at single-cell resolution. Transgenic mice express a reporter comprising GFP fused to human histone H2B und |
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