File:Mouse hematopoietic stem cell.gif

Mouse hematopoietic stem cell locations

AGM - aorta–gonad–mesenepheros region

"The major site of hematopoiesis transitions from the fetal liver to the spleen and bone marrow late in fetal development. To date, experiments have not been performed to evaluate functionally the migration and seeding of hematopoietic stem cells (HSCs) during this period in ontogeny."

Reference

<pubmed>15024423</pubmed>| Plos Biol.

Citation: Christensen JL, Wright DE, Wagers AJ, Weissman IL (2004) Circulation and Chemotaxis of Fetal Hematopoietic Stem Cells. PLoS Biol 2(3): e75. doi:10.1371/journal.pbio.0020075

Academic Editor: Douglas Melton, Harvard University

Received: August 22, 2003; Accepted: January 7, 2004; Published: March 16, 2004

Copyright: © 2004 Christensen et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.