File:Thyroid signaling - endocrine-disrupting chemicals.jpg
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Figure 1. Thyroid signaling pathway and endocrine-disrupting chemicals. Groups of chemicals act at: PCB and PCDD: 5, 7; PBDEs: 5, 6, 7, 8; pesticides: 4, 5, 7; PFASs: 5, 6; NIS: 3; BPA: 2, 7; phthalates: 1, 2, 5, 8. Abbreviations: BPA, bisphenol A; NIS, sodium iodide symporters; PBDE, polybrominated diphenyl ethers; PCB, polychlorinated biphenyl; PCDD, polychlorinated dibenzodioxins; PFAS, perfluoroalkyl substances; TRH, thyroid-releasing hormone; TSH, thyroid-stimulating hormone; T4, thyroxine; T3, triiodothyronine. Image of thyroid: by P. J. Witt, AU from the Noun Project, Creative Commons.
Reference
Ghassabian A & Trasande L. (2018). Disruption in Thyroid Signaling Pathway: A Mechanism for the Effect of Endocrine-Disrupting Chemicals on Child Neurodevelopment. Front Endocrinol (Lausanne) , 9, 204. PMID: 29760680 DOI.
Copyright: © 2018 Ghassabian and Trasande. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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current | 16:57, 21 May 2018 | ![]() | 800 × 889 (74 KB) | Z8600021 (talk | contribs) | Figure 1. Thyroid signaling pathway and endocrine-disrupting chemicals. Groups of chemicals act at: PCB and PCDD: 5, 7; PBDEs: 5, 6, 7, 8; pesticides: 4, 5, 7; PFASs: 5, 6; NIS: 3; BPA: 2, 7; phthalates: 1, 2, 5, 8. Abbreviations: BPA, bisphenol A; NIS... |
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