Sensory - Vision Abnormalities
From Embryology
Introduction
These notes introduce the abnormal development of the eye and vision associated structures.
Anophthalmia (absence of an eye) and microphthalmia (small eye within the orbit) have a combined birth prevalence of approximately 30 per 100,000 population. (More? Verma AS, Fitzpatrick DR., 2007)
Genetic factors include developmental transcription factors required for inductive/developmental events in the structure of the eye and retina development.
Environmental factors include gestational-acquired infections, maternal vitamin A deficiency, smoking, X-ray exposure, solvent misuse and thalidomide exposure.
