Talk:Ultrasound - Nuchal Translucency
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Cite this page: Hill, M.A. (2026, October 4) Embryology Ultrasound - Nuchal Translucency. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Talk:Ultrasound_-_Nuchal_Translucency |
2015
Normal reference range of fetal nuchal translucency thickness in pregnant women in the first trimester, one center study
J Res Med Sci. 2015 Oct;20(10):969-73. doi: 10.4103/1735-1995.172786.
Sharifzadeh M1, Adibi A1, Kazemi K2, Hovsepian S3.
Abstract
BACKGROUND: Considering that establishment of reference value of nuchal translucency (NT)-related to the crown rump length (CRL) during the first trimester will be helpful for determining an appropriate cutoff level for screening of increased NT thickness-related abnormalities, we determined the NT thickness and investigated its relation with different chromosomal and nonchromosomal abnormalities among a large sample size of pregnant Iranian women. MATERIALS AND METHODS: In this analytic cross-sectional study, pregnant women who were in their first trimester were enrolled at their antenatal visit. Using an abdominal ultrasonography, the fetal NT thickness of the studied population was measured. Those with increased NT thickness were determined. The reference value of NT thickness (5th, 25th, 50th, 75th, and 95th percentiles) within each 5-mm range of CRL and during the 11th, 12th, and 13th gestational weeks were determined. The presences of the different chromosomal and nonchromosomal abnormalities were compared in women with different percentiles of NT thickness who underwent amniocentesis and those who did not. RESULTS: 1,614 pregnant women were evaluated. The mean NT thickness was 1.30 ± 0.54 mm. Increased NT thickness >2 mm and >95th percentile according to their gestational age (GA) was detected in 89 (5.5%) and 58 (3.6%) pregnant women. The reference 95th percentile value range for NT was 1.8-2.35 and increased NT thickness according to our obtained values was associated significantly with chromosomal abnormalities. CONCLUSION: The obtained reference range in our studied population was different from that reported for other ethnic groups and it is suggested that using this values are more favorable for screening of chromosomal abnormalities during the first trimester of pregnancy than the recommended single cutoff value. KEYWORDS: Crown rump length (CRL); nuchal translucency (NL); reference values
PMID 26929762 PMCID: PMC4746871 DOI: 10.4103/1735-1995.172786
2013
Nuchal translucency in normal fetus and its variation with increasing crown rump length (CRL) and gestational age. Karki S, Joshi KS, Tamrakar SR, Regmi S, Khanal K. Kathmandu Univ Med J (KUMJ). 2013 Oct-Dec;11(44):282-6. PMID 24899320 Similar articles Select item 23141162
Distribution of nuchal translucency thickness in Japanese fetuses. Hasegawa J, Nakamura M, Hamada S, Matsuoka R, Ichizuka K, Sekizawa A, Okai T. J Obstet Gynaecol Res. 2013 Apr;39(4):766-9. doi: 10.1111/j.1447-0756.2012.02037.x. PMID 23107008 Similar articles Select item 14966338
2012
[Distribution and normal reference range of fetal nuchal translucency thickness in Kunming pregnant women in the first trimester]. Sun Q, Xu J, Hu SQ, Chen M, Ma RM, Lau TK, Zhang L, Xiao X, Qian Y, Guo Z. Zhonghua Fu Chan Ke Za Zhi. 2012 Jul;47(7):514-7. Chinese. PMID 23141162 Similar articles Select item 23107008
2004
The distribution of fetal nuchal translucency thickness in normal Korean fetuses. Chung JH, Yang JH, Song MJ, Cho JY, Lee YH, Park SY, Moon MJ, Lim HJ, Choi JS, Kim JO, Shin JS, Ahn HK, Han JY, Kim MY, Choi KH, Ryu HM. J Korean Med Sci. 2004 Feb;19(1):32-6. PMID 14966338 Free PMC Article
2001
Relationship between fetal nuchal translucency and crown-rump length in an Asian population. Jou HJ, Wu SC, Li TC, Hsu HC, Tzeng CY, Hsieh FJ. Ultrasound Obstet Gynecol. 2001 Feb;17(2):111-4. PMID 11251917 Free Article Similar articles
