Testis Development Movie: Difference between revisions

Revision as of 11:07, 25 February 2018

Embryology - 18 Sep 2026 Expand to Translate
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<html5media height="650" width="350">File:Testis 001.mp4</html5media>

Click Here to play on mobile device

Testis and Ductus Deferens Development

This animation shows the process of early testis and ductus deferens (vas deferens) development.

Paramesonephric duct (red left, Müllerian duct) degenerates under the influence of Anti-Müllerian hormone (AMH) secreted by sertoli cells (differentiated by SRY expression). OMIM - AMH
Mesonephric duct (purple, Wolffian duct) differentiates under the influence of testosterone secreted by Leydig cells. Within the testes these mesonephric tubules grow towards the medullary sex cords and will form the rete teste. The mesonephric duct extending out of the gonad forms the ductus deferens.
Medullary sex cords (orange) form testis cords.
- these later differentiate into solid seminiferous tubules that during puberty become hollow and actively produce spermatozoa.
The surrounding connective tissue (pink) differentiates to form stromal cells.
The tunica albuginea (white) covers the testis and bands extend inward to form connective tissue septa.

Compare this animation with that for ovary development animation.

Embryonically, both gonads (testis and ovary) and internal genital tracts (ductus deferens and uterus) begin with the same basic elements that have divergent pathways under the initial influence of the sex chromosomes (Y and X).

Genital Movie Links

Historic Embryology - Genital
General: 1901 Urinogenital Tract \| 1902 The Uro-Genital System \| 1904 Ovary and Testis \| 1912 Urinogenital Organ Development \| 1914 External Genitalia \| 1921 Urogenital Development \| 1921 External Genital \| 1942 Sex Cords \| 1953 Germ Cells \| Historic Embryology Papers \| Historic Disclaimer
Female: 1904 Ovary and Testis \| 1904 Hymen \| 1912 Urinogenital Organ Development \| 1914 External Genitalia \| 1914 Female \| 1921 External Genital \| 1927 Female Foetus 15 cm \| 1927 Vagina \| 1932 Postnatal Ovary
Male: 1887-88 Testis \| 1904 Ovary and Testis \| 1904 Leydig Cells \| 1906 Testis vascular \| 1909 Prostate \| 1912 Prostate \| 1914 External Genitalia \| 1915 Cowper’s and Bartholin’s Glands \| 1920 Wolffian tubules \| 1935 Prepuce \| 1935 Wolffian Duct \| 1942 Sex Cords \| 1943 Testes Descent \| Historic Embryology Papers \| Historic Disclaimer

Anti-mullerian hormone (AMH) - (19p13.3)
- also called mullerian-inhibiting substance (MIS) or factor (MIF).
- regression of Mullerian ducts in the male embryo
- role in Leydig cell differentiation and function
- follicular development in adult females.
- Ligand of TGF-beta (transforming growth factor-beta) superfamily.
- Receptor - binds to the anti-Mullerian hormone receptor type 2.
- activate SMAD family transcription factors that regulate gene expression.
- preproprotein proteolytically processed to generate N- and C-terminal cleavage products, that homodimerize and associate to form a biologically active noncovalent complex.
- Protein Atlas

Testis histology

Testis historic drawing

Note these 2 images are anatomically the mirror image of the above animation.

Glossary Links: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Movies

Cite this page: Hill, M.A. (2026, September 18) Embryology Testis Development Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Testis_Development_Movie

What Links Here?

@@ Line 29: / Line 29: @@
 {{Genital Links}}
-* Anti-mullerian hormone ([https://www.genenames.org/cgi-bin/gene_symbol_report?match=AMH AMH]) - (19p13.3) also called mullerian-inhibiting substance (MIS) or factor (MIF). No biologic action of AMH after birth.
+* Anti-mullerian hormone ([https://www.genenames.org/cgi-bin/gene_symbol_report?match=AMH AMH]) - (19p13.3)
+** also called mullerian-inhibiting substance (MIS) or factor (MIF).
+** regression of Mullerian ducts in the male embryo
+** role in Leydig cell differentiation and function
+** follicular development in adult females.
+** Ligand of TGF-beta (transforming growth factor-beta) superfamily.
+** Receptor - binds to the anti-Mullerian hormone receptor type 2.
+** activate SMAD family transcription factors that regulate gene expression.
+** preproprotein proteolytically processed to generate N- and C-terminal cleavage products, that homodimerize and associate to form a biologically active noncovalent complex.
+** [https://www.proteinatlas.org/ENSG00000104899-AMH/cell Protein Atlas]
 |}