File:Implantation cartoon 02.jpg: Difference between revisions

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Decidualization involves coordination of several processes, including polyploidy, and several types of molecules, such as cytokine receptors, enzymes, morphogens, hormones and transcription factors.  
Decidualization involves coordination of several processes, including polyploidy, and several types of molecules, such as cytokine receptors, enzymes, morphogens, hormones and transcription factors.  
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* '''ADM''' - adrenomedullin
* '''ADM''' - adrenomedullin
* '''BV''' - blood vessel
* '''BV''' - blood vessel

Revision as of 16:20, 17 March 2014

Key Molecules for Decidualization

Legend
Key molecules for decidualization are depicted in this hybrid cartoon as gathered from mouse and human studies. The decidua is composed of differentiated stromal (decidual) cells, many of which are terminally differentiated (polyploid).

Decidualization involves coordination of several processes, including polyploidy, and several types of molecules, such as cytokine receptors, enzymes, morphogens, hormones and transcription factors.

  • ADM - adrenomedullin
  • BV - blood vessel
  • DEDD - death effector domain–containing protein
  • IL-11Rα - interleukin 11 receptor α
  • mTORC1 - mammalian target of rapamycin complex 1
  • SGK1 - serum- and glucocorticoid-inducible kinase 1
  • Sphk1/2 - sphingosine kinase 1/2


Reference

<pubmed>23223073</pubmed>| Nat Med

Copyright

Reprinted by permission from Macmillan Publishers Ltd: Nature Medicine (Mechanisms of implantation: strategies for successful pregnancy. Cha J, Sun X, Dey SK. Nat Med. 2012 Dec;18(12):1754-67. doi: 10.1038/nm.3012. Review. PMID 23223073), copyright (2012)

Nm.3012-F2.jpg

File history

Yi efo/eka'e gwa ebo wo le nyangagi wuncin ye kamina wunga tinya nan

GwalagizhiNyangagiDimensionsUserComment
current18:47, 18 March 2013Thumbnail for version as of 18:47, 18 March 2013950 × 1,000 (161 KB)Z8600021 (talk | contribs) Key molecules for decidualization are depicted in this hybrid cartoon as gathered from mouse and human studies. The decidua is composed of differentiated stromal (decidual) cells, many of which are terminally differentiated (polyploid). Decidualizatio...