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(Skeletal malformations are present in E18.5 and in newborn Ktcn-PITX2 mice. Alizarin Red and Alcian Blue stainings of forelimbs from E18.5 (upper section) and newborn (lower section) mice. Forelimbs of E18.5 and newborn Ktcn-PITX2 mice display a diminis)
 
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Skeletal malformations are present in E18.5 and in newborn Ktcn-PITX2 mice.
==Skeletal malformations are present in E18.5 and in newborn Ktcn-PITX2 mice==


Alizarin Red and Alcian Blue stainings of forelimbs from E18.5 (upper section) and newborn (lower section) mice. Forelimbs of E18.5 and newborn Ktcn-PITX2 mice display a diminished deltoid tuberosity (*).  
Alizarin Red and Alcian Blue stainings of forelimbs from E18.5 (upper section) and newborn (lower section) mice. Forelimbs of E18.5 and newborn Ktcn-PITX2 mice display a diminished deltoid tuberosity (*).  
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Newborn Ktcn-PITX2 mice also exhibit a thickening of the distal humerus, which tends to partly dislocate the radius anteriorly and also slightly dislocate the proximal part of the ulna in a more lateral-dorsal position, which makes the ulna appear twisted (arrows).
Newborn Ktcn-PITX2 mice also exhibit a thickening of the distal humerus, which tends to partly dislocate the radius anteriorly and also slightly dislocate the proximal part of the ulna in a more lateral-dorsal position, which makes the ulna appear twisted (arrows).


1471-213X-8-25-2.jpg
===Reference===
 
 
Holmberg et al. BMC Developmental Biology 2008 8:25  doi:10.1186/1471-213X-8-25 [http://www.biomedcentral.com/1471-213X/8/25 BMC Developmental Biology]


http://www.biomedcentral.com/1471-213X/8/25


Holmberg et al. BMC Developmental Biology 2008 8:25  doi:10.1186/1471-213X-8-25
====Copyright====


© 2008 Holmberg et al; licensee BioMed Central Ltd.
© 2008 Holmberg et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
1471-213X-8-25-2.jpg
[[Category:Mouse]] [[Category:Limb]] [[Category:Bone]]

Latest revision as of 00:11, 18 January 2013

Skeletal malformations are present in E18.5 and in newborn Ktcn-PITX2 mice

Alizarin Red and Alcian Blue stainings of forelimbs from E18.5 (upper section) and newborn (lower section) mice. Forelimbs of E18.5 and newborn Ktcn-PITX2 mice display a diminished deltoid tuberosity (*).

Newborn Ktcn-PITX2 mice also exhibit a thickening of the distal humerus, which tends to partly dislocate the radius anteriorly and also slightly dislocate the proximal part of the ulna in a more lateral-dorsal position, which makes the ulna appear twisted (arrows).

Reference

Holmberg et al. BMC Developmental Biology 2008 8:25 doi:10.1186/1471-213X-8-25 BMC Developmental Biology


Copyright

© 2008 Holmberg et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


1471-213X-8-25-2.jpg

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current20:34, 14 September 2009Thumbnail for version as of 20:34, 14 September 2009600 × 812 (71 KB)S8600021 (talk | contribs)Skeletal malformations are present in E18.5 and in newborn Ktcn-PITX2 mice. Alizarin Red and Alcian Blue stainings of forelimbs from E18.5 (upper section) and newborn (lower section) mice. Forelimbs of E18.5 and newborn Ktcn-PITX2 mice display a diminis

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