Talk:Draft 2016: Difference between revisions

Revision as of 18:35, 26 February 2016

Location throughout the entire body - concentrated in axilla, groin, lung, gastrointestinal tract mesenteries
Small (1 mm - 2 cm) encapsulated organ (diffuse lymphoid tissue - no capsule)
Antigen transformed lymphocytes from the blood
In lymph vessel pathways “filter” lymph
- Afferent - towards node (A - arrives at the node)
- Efferent - away from node (E - exits the node)

Mesenteric lymph nodes

Lymph Node Functions
In lymph vessel pathways “filter” (surveillance) lymph Immune - detect infections from peripheral tissues skin, respiratory tract, gastrointestinal tract, etc. secondary lymphoid organ return extracellular fluid to circulation

Simplified structure

Lymphocyte (T and B) Traffic

Lymph pathway

Watch T and B Lymphocytes Move

‎‎Lymph Node 7

‎‎Lymph Node 8

Fetal thymus	Young medulla	Young cortex

Connective Tissue

Capsule - dense connective tissue (irregular CT, some adipocytes))
Trabeculae - dense connective tissue
Reticular Tissue - Reticular cells and fibers, supporting meshwork (collagen type III)
- Reticular cell produces reticular fibers (collagen type III) and surrounds the fibers with its cytoplasm
- reticular fibbers can also be produced by fibroblasts

Important - Please note that the lymphocytes exit from the node by efferent lymphatic vessels.

‎‎Lymph Node 7

T and B motility

‎‎Lymph Node 8

T and B interaction

High Endothelial Venules

Links: Immunobiology - Figure 1.8. Organization of a lymph node

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 |-
 | [[File:Lymph node structure 02.jpg]]
-'''Lymph pathway'''
+| '''Lymph pathway'''
 # Afferent vessel
 # Subcapsular sinus
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 # Medullary sinus
 # Efferent vessel
-| {{Lymph Node Movie 7}}{{Lymph Node Movie 8}}
+{| class="wikitable mw-collapsible mw-collapsed"
+! colspan=2|Watch T and B Lymphocytes Move&nbsp;
-T and B motility
+| {{Lymph Node Movie 7}}
+| {{Lymph Node Movie 8}}
+|}
 |}