Testis Development Movie: Difference between revisions

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Embryology - 19 Sep 2026 Expand to Translate
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<mediaplayer width='350' height='650' image="http://embryology.med.unsw.edu.au/embryology/images/f/fa/Gonad-icon.jpg">File:Testis 001.mp4</mediaplayer>

Testis and Ductus Deferens Development

This animation shows the process of early testis and ductus deferens (vas deferens) development.

Paramesonephric duct (red left, Müllerian duct) degenerates under the influence of Mullerian duct inhibitory factor (MDIF) secreted by sertoli cells (differentiated by SRY expression).
Mesonephric duct (purple, Wolffian duct) differentiates under the influence of testosterone secreted by Leydig cells. Within the testes these mesonephric tubules grow towards the medullary sex cords and will form the rete teste. The mesonephric duct extending out of the gonad forms the ductus deferens.
Medullary sex cords (orange) form testis cords.
- these later differentiate into solid seminiferous tubules that during puberty become hollow and actively produce spermatozoa.
The surrounding connective tissue (pink) differentiates to form stromal cells.
The tunica albuginea (white) covers the testis and bands extend inward to form connective tissue septa.

Compare this animation with that for ovary development animation.

Embryonically, both gonads (testis and ovary) and internal genital tracts (ductus deferens and uterus) begin with the same basic elements that have divergent pathways under the initial influence of the sex chromosomes (Y and X).

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Cite this page: Hill, M.A. (2026, September 19) Embryology Testis Development Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Testis_Development_Movie

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-* The <font color=red>'''paramesonephric duct'''</font> (red, left) degenerates under the influence of Mullerian duct inhibitory factor (MDIF) secreted by sertoli cells (differentiated by SRY expression).
+* <font color=red>'''Paramesonephric duct'''</font> (red left, Müllerian duct) degenerates under the influence of Mullerian duct inhibitory factor (MDIF) secreted by sertoli cells (differentiated by SRY expression).
-* The <font color=darkmagenta>'''mesonephric duct'''</font> (purple) differentiates under the influence of Testosterone secreted by Leydig cells. Within the testes these mesonephric tubules grow towards the medullary sex cords and will form the rete teste. The mesonephric duct extending out of the gonad forms the ductus deferens.
+* <font color=darkmagenta>'''Mesonephric duct'''</font> (purple, Wolffian duct) differentiates under the influence of testosterone secreted by Leydig cells. Within the testes these mesonephric tubules grow towards the medullary sex cords and will form the rete teste. The mesonephric duct extending out of the gonad forms the ductus deferens.
-* The <font color=orange>'''medullary sex cords'''</font> (orange) form testis cords.
+* <font color=orange>'''Medullary sex cords'''</font> (orange) form testis cords.
 ** these later differentiate into solid seminiferous tubules that during puberty become hollow and actively produce spermatozoa.
 * The surrounding connective tissue (pink) differentiates to form stromal cells.